The SLC30 family of zinc transporters–a review of current understanding of their biological and pathophysiological roles
L Huang, S Tepaamorndech - Molecular aspects of medicine, 2013 - Elsevier
Two families of zinc (Zn2+) transporters are involved in zinc homeostasis in the body, SLC30
(ZnT, zinc transporter) and SLC39 (ZIP, Zinc (Zn2+)–Iron (Fe2+) Permease). The two zinc …
(ZnT, zinc transporter) and SLC39 (ZIP, Zinc (Zn2+)–Iron (Fe2+) Permease). The two zinc …
Advances in type 1 diabetes prediction using islet autoantibodies: beyond a simple count
M So, C Speake, AK Steck, M Lundgren… - Endocrine …, 2021 - academic.oup.com
Islet autoantibodies are key markers for the diagnosis of type 1 diabetes. Since their
discovery, they have also been recognized for their potential to identify at-risk individuals …
discovery, they have also been recognized for their potential to identify at-risk individuals …
Novel subgroups of adult-onset diabetes and their association with outcomes: a data-driven cluster analysis of six variables
E Ahlqvist, P Storm, A Käräjämäki… - The lancet Diabetes & …, 2018 - thelancet.com
Background Diabetes is presently classified into two main forms, type 1 and type 2 diabetes,
but type 2 diabetes in particular is highly heterogeneous. A refined classification could …
but type 2 diabetes in particular is highly heterogeneous. A refined classification could …
Systematic population screening, using biomarkers and genetic testing, identifies 2.5% of the UK pediatric diabetes population with monogenic diabetes
M Shepherd, B Shields, S Hammersley… - Diabetes …, 2016 - Am Diabetes Assoc
OBJECTIVE Monogenic diabetes is rare but is an important diagnosis in pediatric diabetes
clinics. These patients are often not identified as this relies on the recognition of key clinical …
clinics. These patients are often not identified as this relies on the recognition of key clinical …
Absence of islet autoantibodies and modestly raised glucose values at diabetes diagnosis should lead to testing for MODY: lessons from a 5-year pediatric Swedish …
OBJECTIVE Identifying maturity-onset diabetes of the young (MODY) in pediatric
populations close to diabetes diagnosis is difficult. Misdiagnosis and unnecessary insulin …
populations close to diabetes diagnosis is difficult. Misdiagnosis and unnecessary insulin …
Advances in the cellular immunological pathogenesis of type 1 diabetes
M Li, LJ Song, XY Qin - Journal of cellular and molecular …, 2014 - Wiley Online Library
Type 1 diabetes is an autoimmune disease caused by the immune‐mediated destruction of
insulin‐producing pancreatic β cells. In recent years, the incidence of type 1 diabetes …
insulin‐producing pancreatic β cells. In recent years, the incidence of type 1 diabetes …
[HTML][HTML] Multiplex agglutination-PCR (ADAP) autoantibody assays compared to radiobinding autoantibodies in type 1 diabetes and celiac disease
A Lind, F de Jesus Cortez, A Ramelius… - Journal of …, 2022 - Elsevier
Abstract Multiplex Antibody-Detection by Agglutination-PCR (ADAP) assay was compared to
singleplex standard radiobinding assays (RBA) to detect autoantibodies against insulin …
singleplex standard radiobinding assays (RBA) to detect autoantibodies against insulin …
Next-Generation Sequencing Reveals That HLA-DRB3, -DRB4, and -DRB5 May Be Associated With Islet Autoantibodies and Risk for Childhood Type 1 Diabetes
LP Zhao, S Alshiekh, M Zhao, A Carlsson… - Diabetes, 2016 - Am Diabetes Assoc
The possible contribution of HLA-DRB3,-DRB4, and-DRB5 alleles to type 1 diabetes risk
and to insulin autoantibody (IAA), GAD65 (GAD autoantibody [GADA]), IA-2 antigen (IA-2A) …
and to insulin autoantibody (IAA), GAD65 (GAD autoantibody [GADA]), IA-2 antigen (IA-2A) …
Thyroid and islet autoantibodies predict autoimmune thyroid disease at type 1 diabetes diagnosis
B Jonsdottir, C Larsson, A Carlsson… - The Journal of …, 2017 - academic.oup.com
Context: Screening of autoimmune thyroid disease in children with type 1 diabetes is
important but varies between clinics. Objective: To determine the predictive value of thyroid …
important but varies between clinics. Objective: To determine the predictive value of thyroid …
Triple specificity of ZnT8 autoantibodies in relation to HLA and other islet autoantibodies in childhood and adolescent type 1 diabetes
C Andersson, F Vaziri‐Sani, AJ Delli… - Pediatric …, 2013 - Wiley Online Library
Objective To establish the diagnostic sensitivity of and the relationships between
autoantibodies to all three Zinc transporter 8 (Zinc transporter 8 autoantibody to either one …
autoantibodies to all three Zinc transporter 8 (Zinc transporter 8 autoantibody to either one …