[HTML][HTML] Role of PI3K/AKT pathway in cancer: the framework of malignant behavior

N Jiang, Q Dai, X Su, J Fu, X Feng, J Peng - Molecular biology reports, 2020 - Springer
Given that the PI3K/AKT pathway has manifested its compelling influence on multiple
cellular process, we further review the roles of hyperactivation of PI3K/AKT pathway in …

Significance of miRNAs on the thyroid cancer progression and resistance to treatment with special attention to the role of cross-talk between signaling pathways

AS Doghish, HA El-Mahdy, A Ismail, M Hegazy… - … -Research and Practice, 2023 - Elsevier
Thyroid cancer (TC) is the most prevalent endocrine malignant tumor. It has many types, the
Papillary thyroid cancer (PTC)(most common and follicular thyroid carcinoma (FTC). Several …

Extracellular vesicles and particles impact the systemic landscape of cancer

S Lucotti, CM Kenific, H Zhang, D Lyden - The EMBO journal, 2022 - embopress.org
Intercellular cross talk between cancer cells and stromal and immune cells is essential for
tumor progression and metastasis. Extracellular vesicles and particles (EVPs) are a …

[HTML][HTML] MiR-145: a potential biomarker of cancer migration and invasion

WX Xu, Z Liu, F Deng, DD Wang, XW Li… - American journal of …, 2019 - ncbi.nlm.nih.gov
MircoRNAs (miRNAs) are a diverse family of highly-conserved small non-coding RNAs,
which range from approximately 18 to 25 nucleotides in size. They regulate gene expression …

Plasma exosomal miR-21 and miR-181a differentiates follicular from papillary thyroid cancer

R Samsonov, V Burdakov, T Shtam, Z Radzhabovа… - Tumor Biology, 2016 - Springer
Thyroid cancer (TC) is the most common endocrine malignancy and its incidence has
increased over the last few decades. As has been revealed by a number of studies, TC …

[HTML][HTML] Regulatory mechanisms of miR-145 expression and the importance of its function in cancer metastasis

T Zeinali, B Mansoori, A Mohammadi… - Biomedicine & …, 2019 - Elsevier
MicroRNAs are post-transcriptional mediators of gene expression and regulation, which play
influential roles in tumorigenesis and cancer metastasis. The expression of tumor …

Function of microRNA-145 and mechanisms underlying its role in malignant tumor diagnosis and treatment

D Ye, Z Shen, S Zhou - Cancer management and research, 2019 - Taylor & Francis
miRNAs are single-stranded small RNAs that do not encode proteins. They can combine
complementarily with the 3′-UTRs of target gene mRNA molecules to promote targeted …

[HTML][HTML] MicroRNAs as the critical regulators of cell migration and invasion in thyroid cancer

AA Hamidi, N Taghehchian, Z Basirat, AS Zangouei… - Biomarker …, 2022 - Springer
Thyroid cancer (TC) is one of the most frequent endocrine malignancies that is more
common among females. Tumor recurrence is one of the most important clinical …

MiR-150 attenuates LPS-induced acute lung injury via targeting AKT3

P Li, Y Yao, Y Ma, Y Chen - International immunopharmacology, 2019 - Elsevier
Acute lung injury (ALI) and its severe manifestation of acute respiratory distress syndrome
(ARDS) in human lung are induced by inflammatory cytokines and endogenous factors such …

MiR‐145 in cancer therapy resistance and sensitivity: A comprehensive review

W Xu, Y Hua, F Deng, D Wang, Y Wu, W Zhang… - Cancer …, 2020 - Wiley Online Library
MircoRNA (miRNA) are a group of small, non–coding, regulatory RNA with an average
length of approximately 22 nucleotides, which mostly modulate gene expression post …