Plants evolve to synthesize various natural metabolites to protect themselves against
threats, such as insects, predators, microorganisms, and environmental conditions (such as …

Ribosome-inactivating proteins (RIPs) are a class of cytotoxic rRNA N-glycosylase, which
widely exist in higher plants in different taxonomy, including many traditional Chinese …

Ageritin from poplar mushrooms is a specific endonuclease that hydrolyzes a single
phosphodiester bond located in the sarcin-ricin loop (SRL) of the large rRNA, thereby …

Saporin is a type 1 ribosome-inactivating protein widely used as toxic payload in the
construction of targeted toxins, chimeric molecules formed by a toxic portion linked to a …

Sodin 5 is a type 1 ribosome-inactivating protein isolated from the seeds of Salsola soda L.,
an edible halophytic plant that is widespread in southern Europe, close to the coast. This …

Ribosome-inactivating proteins (RIPs) are plant toxins that were identified for their ability to
irreversibly damage ribosomes, thereby causing arrest of protein synthesis and induction of …

Ribosome inactivating proteins (RIPs) are specific N-β-glycosylases that are well-
characterized in plants. Their enzymatic action is to damage ribosomes, thereby blocking …

Background Anticancer genes are an endogenous defense against transformed cells as
they impose antineoplastic effects upon ectopic expression. Profiling the expression of these …

Toxin proteins are secreted by most pathogens as an integral part of pathogenic mechanism
(s). The toxins act by either damaging the host cell membrane (for example, pore-forming …

The researchers found that by radiotherapy, the increase in MST4 in tumors can be reversed
to increase the death of tumor cells. MST4, as an autophagy-associated protein, plays a …