This review considers computational psychiatry from a particular viewpoint: namely, a
commitment to explaining psychopathology in terms of pathophysiology. It rests on the …

Analysis and interpretation of studies on cognitive and affective dysregulation often draw
upon the network paradigm, especially the Triple Network Model, which consists of the …

This paper considers functional integration in the brain from a computational perspective.
We ask what sort of neuronal message passing is mandated by active inference—and what …

This technical note describes some Bayesian procedures for the analysis of group studies
that use nonlinear models at the first (within-subject) level–eg, dynamic causal models–and …

Twenty years have passed since the dysconnection hypothesis was first proposed (Friston
and Frith, 1995; Weinberger, 1993). In that time, neuroscience has witnessed tremendous …

An argument for a Copernican revolution in our consideration of mental features—a shift in
which the world-brain problem supersedes the mind-body problem. Philosophers have long …

Belief updating is a relatively nascent field of research that examines how people adjust
their beliefs in light of new evidence. So far, belief updating has been investigated in partly …

Background Diminished synaptic gain—the sensitivity of postsynaptic responses to neural
inputs—may be a fundamental synaptic pathology in schizophrenia. Evidence for this is …

The brain is a predictive machine. Converging data suggests a diametric predictive strategy
from autism spectrum disorders (ASD) to schizophrenic spectrum disorders (SSD). Whereas …

The central and autonomic nervous systems can be defined by their anatomical, functional
and neurochemical characteristics, but neither functions in isolation. For example …