The role of oxidative stress in the pathogenesis of vitiligo: a culprit for melanocyte death
Y Xuan, Y Yang, L Xiang… - Oxidative Medicine and …, 2022 - Wiley Online Library
Vitiligo is a common chronic acquired pigmentation disorder characterized by loss of
pigmentation. Among various hypotheses proposed for the pathogenesis of vitiligo, oxidative …
pigmentation. Among various hypotheses proposed for the pathogenesis of vitiligo, oxidative …
Roles of extracellular HSPs as biomarkers in immune surveillance and immune evasion
EA Taha, K Ono, T Eguchi - International Journal of Molecular Sciences, 2019 - mdpi.com
Extracellular heat shock proteins (ex-HSPs) have been found in exosomes, oncosomes,
membrane surfaces, as well as free HSP in cancer and various pathological conditions, also …
membrane surfaces, as well as free HSP in cancer and various pathological conditions, also …
ER chaperone GRP78/BiP translocates to the nucleus under stress and acts as a transcriptional regulator
Cancer cells are commonly subjected to endoplasmic reticulum (ER) stress. To gain survival
advantage, cancer cells exploit the adaptive aspects of the unfolded protein response such …
advantage, cancer cells exploit the adaptive aspects of the unfolded protein response such …
Immunogenic cell death and immunotherapy of multiple myeloma
Over the past decades, immunotherapy has demonstrated a prominent clinical efficacy in a
wide variety of human tumors. For many years, apoptosis has been considered a non …
wide variety of human tumors. For many years, apoptosis has been considered a non …
Origin and consequences of necroinflammation
M Sarhan, WG Land, W Tonnus… - Physiological …, 2018 - journals.physiology.org
When cells undergo necrotic cell death in either physiological or pathophysiological settings
in vivo, they release highly immunogenic intracellular molecules and organelles into the …
in vivo, they release highly immunogenic intracellular molecules and organelles into the …
Near-infrared absorbing Ru (ii) complexes act as immunoprotective photodynamic therapy (PDT) agents against aggressive melanoma
Mounting evidence over the past 20 years suggests that photodynamic therapy (PDT), an
anticancer modality known mostly as a local treatment, has the capacity to invoke a systemic …
anticancer modality known mostly as a local treatment, has the capacity to invoke a systemic …
Updates on the use of liposomes for active tumor targeting in cancer therapy
In the development of cancer chemotherapy, besides the discovery of new anticancer drugs,
a variety of nanocarrier systems for the delivery of previously developed and new …
a variety of nanocarrier systems for the delivery of previously developed and new …
Glucose‐regulated protein (GRP78) is an important cell surface receptor for viral invasion, cancers, and neurological disorders
The 78 kDa glucose‐regulated protein (GRP78) is an endoplasmic reticulum (ER)‐resident
molecular chaperone. GRP78 is a member of the 70 kDa heat shock family of proteins …
molecular chaperone. GRP78 is a member of the 70 kDa heat shock family of proteins …
Post-translational modifications: regulators of neurodegenerative proteinopathies
One of the hallmark features in the neurodegenerative disorders (NDDs) is the accumulation
of aggregated and/or non-functional protein in the cellular milieu. Post-translational …
of aggregated and/or non-functional protein in the cellular milieu. Post-translational …
[HTML][HTML] Platelet membrane-coated nanocarriers targeting plaques to deliver anti-CD47 antibody for atherosclerotic therapy
Atherosclerosis, the principle cause of cardiovascular disease (CVD) worldwide, is mainly
characterized by the pathological accumulation of diseased vascular cells and apoptotic …
characterized by the pathological accumulation of diseased vascular cells and apoptotic …