In situ formation of injectable hydrogels for chronic wound healing

Y Gao, Z Li, J Huang, M Zhao, J Wu - Journal of Materials Chemistry B, 2020 - pubs.rsc.org
Hydrogels have been widely used in wound healing treatment over the past decade.
Injectable hydrogels have become a major research focus due to their unique advantages …

[HTML][HTML] Sustained and targeted delivery of hydrophilic drug compounds: A review of existing and novel technologies from bench to bedside

D Hawthorne, A Pannala, S Sandeman… - Journal of Drug Delivery …, 2022 - Elsevier
The sustained and/or targeted delivery of hydrophilic drugs is an important field within drug
delivery, presenting unique challenges when compared to that of hydrophobic drugs. Yet …

[HTML][HTML] Simvastatin/hydrogel-loaded 3D-printed titanium alloy scaffolds suppress osteosarcoma via TF/NOX2-associated ferroptosis while repairing bone defects

Z Jing, W Yuan, J Wang, R Ni, Y Qin, Z Mao, F Wei… - Bioactive materials, 2024 - Elsevier
Postoperative anatomical reconstruction and prevention of local recurrence after tumor
resection are two vital clinical challenges in osteosarcoma treatment. A three-dimensional …

[HTML][HTML] Practical strategy to construct anti-osteosarcoma bone substitutes by loading cisplatin into 3D-printed titanium alloy implants using a thermosensitive hydrogel

Z Jing, R Ni, J Wang, X Lin, D Fan, Q Wei, T Zhang… - Bioactive Materials, 2021 - Elsevier
Surgical resection and perioperative adjuvant chemotherapy-based therapies have
improved the prognosis of patients with osteosarcoma; however, intraoperative bone …

Biodegradable hydrophobic injectable polymers for drug delivery and regenerative medicine

Y Arun, R Ghosh, AJ Domb - Advanced Functional Materials, 2021 - Wiley Online Library
Biodegradable, hydrophobic, and injectable liquid polymers are capable of achieving the
minimally invasive, sustained, and local release of drugs. These hydrophobic injectable …

Intraocular nano-microscale drug delivery systems for glaucoma treatment: design strategies and recent progress

Y Shen, J Sun, X Sun - Journal of Nanobiotechnology, 2023 - Springer
Glaucoma is a leading cause of irreversible visual impairment and blindness, affecting over
76.0 million people worldwide in 2020, with a predicted increase to 111.8 million by 2040 …

Smart nano-micro platforms for ophthalmological applications: The state-of-the-art and future perspectives

Q Lyu, L Peng, X Hong, T Fan, J Li, Y Cui, H Zhang… - Biomaterials, 2021 - Elsevier
Smart nano-micro platforms have been extensively applied for diverse biomedical
applications, mostly focusing on cancer therapy. In comparison with conventional …

[HTML][HTML] Hydrogel delivery of DNase I and liposomal vancomycin to eradicate fracture-related methicillin-resistant staphylococcus aureus infection and support …

J Li, SSY Leung, YL Chung, SKH Chow, V Alt, M Rupp… - Acta Biomaterialia, 2023 - Elsevier
Fracture-related infection (FRI) is a devastating complication in orthopedic surgery. A recent
study showed that FRI causes more severe infection and further delays healing in …

Nano-drug delivery systems in oral cancer therapy: recent developments and prospective

Y Zhang, Y Wu, H Du, Z Li, X Bai, Y Wu, H Li, M Zhou… - Pharmaceutics, 2023 - mdpi.com
Oral cancer (OC), characterized by malignant tumors in the mouth, is one of the most
prevalent malignancies worldwide. Chemotherapy is a commonly used treatment for OC; …

Synthesis and characterizations of zwitterionic copolymer hydrogels with excellent lubrication behavior

Z Wang, J Li, Y Liu, J Luo - Tribology International, 2020 - Elsevier
Various studies on hydrogel applications as cartilage substitutes and artificial joints have
been previously conducted. In this study, a copolymer hydrogel comprising zwitterionic …