The proper processing, export, localization, translation, and degradation of mRNAs are necessary for regulation of gene expression. These processes are controlled by mRNA …
L Weill, E Belloc, FA Bava, R Méndez - Nature structural & molecular …, 2012 - nature.com
Beyond the well-known function of poly (A) tail length in mRNA stability, recent years have witnessed an explosion of information about how changes in tail length and the selection of …
N Chesley, S Flood - Journal of Marriage and Family, 2017 - Wiley Online Library
Abstract The authors analyze American Time Use Survey data to examine patterns in domestic work among at‐home and breadwinner parents to gauge how time availability …
The removal of the 5′ cap structure by the decapping enzyme DCP2 inhibits translation and generally commits the mRNA to irreversible 5′-to-3′ exonucleolytic degradation by …
SW Eichhorn, AO Subtelny, I Kronja, JC Kwasnieski… - Elife, 2016 - elifesciences.org
Because maturing oocytes and early embryos lack appreciable transcription, posttranscriptional regulatory processes control their development. To better understand this …
A Kamenska, C Simpson, C Vindry… - Nucleic acids …, 2016 - academic.oup.com
Abstract 4E-Transporter binds eIF4E via its consensus sequence YXXXXLΦ, shared with eIF4G, and is a nucleocytoplasmic shuttling protein found enriched in P-(rocessing) bodies …
E Szostak, F Gebauer - Briefings in functional genomics, 2013 - academic.oup.com
The regulation of mRNA translation is a major checkpoint in the flux of information from the transcriptome to the proteome. Critical for translational control are the trans-acting factors …
Growing evidence indicates that translational control of specific mRNAs contributes importantly to genetic regulation across the breadth of cellular and developmental …
The CCR4–NOT deadenylase complex is a master regulator of translation and mRNA stability. Its NOT module orchestrates recruitment of the catalytic subunits to target mRNAs …