HIV-associated cancers and lymphoproliferative disorders caused by Kaposi sarcoma herpesvirus and Epstein-Barr virus

KA Lurain, R Ramaswami, LT Krug… - Clinical Microbiology …, 2024 - journals.asm.org
Within weeks of the first report of acquired immunodeficiency syndrome (AIDS) in 1981, it
was observed that these patients often had Kaposi sarcoma (KS), a hitherto rarely seen skin …

Clinical management of Kaposi sarcoma herpesvirus-associated diseases: An update on disease manifestations and treatment strategies

R Patel, K Lurain, R Yarchoan… - Expert Review of Anti …, 2023 - Taylor & Francis
Introduction Kaposi sarcoma herpes virus (KSHV) is associated with several diseases
including Kaposi sarcoma, a form of multicentric Castleman's disease, primary effusion …

Insight into oncogenic viral pathways as drivers of viral cancers: implication for effective therapy

AME Elkhalifa, SU Nabi, OS Shah, SM Bashir… - Current …, 2023 - mdpi.com
As per a recent study conducted by the WHO, 15.4% of all cancers are caused by infectious
agents of various categories, and more than 10% of them are attributed to viruses. The …

Hypoxia and hypoxia‐inducible factors in Kaposi sarcoma‐associated herpesvirus infection and disease pathogenesis

DA Davis, P Shrestha… - Journal of Medical Virology, 2023 - Wiley Online Library
Kaposi sarcoma‐associated herpesvirus (KSHV) is the causative agent of Kaposi sarcoma
and several other tumors and hyperproliferative diseases seen predominantly in human …

A Role for the Chicken Interferon-Stimulated Gene CMPK2 in the Host Response Against Virus Infection

X Li, Y Feng, W Liu, L Tan, Y Sun, C Song… - Frontiers in …, 2022 - frontiersin.org
Virus infection can lead to the production of interferon, which activates the JAK/STAT
pathway and induces the expression of multiple downstream interferon-stimulated genes …

Folate-targeted nanocarriers co-deliver ganciclovir and miR-34a-5p for combined Anti-KSHV therapy

F Li, D Cao, W Gu, D Li, Z Liu, L Cui - International Journal of Molecular …, 2024 - mdpi.com
Kaposi's sarcoma-associated herpesvirus (KSHV) can cause a variety of malignancies.
Ganciclovir (GCV) is one of the most efficient drugs against KSHV, but its non-specificity can …

Molecular mechanism underlying role of the XBP1s in cardiovascular diseases

S Liu, H Ding, Y Li, X Zhang - Journal of Cardiovascular Development and …, 2022 - mdpi.com
Spliced X-box binding protein-1 (XBP1s) is a protein that belongs to the cAMP-response
element-binding (CREB)/activating transcription factor (ATF) b-ZIP family with a basic-region …

[HTML][HTML] Treatment of tumor-associated macrophages with PD-1 monoclonal antibodies affects vascular generation in cervical cancer via the PD-1/IRE1α/SHP2/HIF1α …

X Hao, W Zhao, X Zhang, X Lu, C Wang… - Aging (Albany …, 2024 - pmc.ncbi.nlm.nih.gov
Objective: To investigate the effect of PD-1 monoclonal antibodies in tumor-associated
macrophages on angiogenesis in cervical cancer and its mechanism of action. Methods …

[图书][B] The ER-Resident Chaperone BiP/GRP78 Is A Pro-viral and Pro-survival Factor In KSHV-Infected Cells

G Najarro - 2023 - search.proquest.com
Abstract Productive Kaposi Sarcoma Associated Herpesvirus (KSHV) infection involves
translating, folding, and modifying abundant viral proteins in the Endoplasmic Reticulum …