Mean platelet volume (MPV): new perspectives for an old marker in the course and prognosis of inflammatory conditions

A Korniluk, OM Koper-Lenkiewicz… - Mediators of …, 2019 - Wiley Online Library
Platelet size has been demonstrated to reflect platelet activity and seems to be a useful
predictive and prognostic biomarker of cardiovascular events. It is associated with a variety …

Platelets, circulating tumor cells, and the circulome

P Kanikarla-Marie, M Lam, DG Menter… - Cancer and Metastasis …, 2017 - Springer
Platelets are cytoplasmic fragments generated by megakaryocytes in the bone marrow and
do not possess a nucleus. They contribute to the “Circulome” consisting of all circulating …

Platelet detection as a new liquid biopsy tool for human cancers

M Chen, L Hou, L Hu, C Tan, X Wang, P Bao… - Frontiers in …, 2022 - frontiersin.org
Cancer is still a leading cause of death worldwide and liquid biopsy is a powerful tool that
can be applied to different stages of cancer screening and treatment. However, as the …

The provocative roles of platelets in liver disease and cancer

P Kanikarla Marie, NW Fowlkes… - Frontiers in …, 2021 - frontiersin.org
Both platelets and the liver play important roles in the processes of coagulation and innate
immunity. Platelet responses at the site of an injury are rapid; their immediate activation and …

Extricating the association between the prognostic factors of colorectal cancer

Y Mohd, B Balasubramanian, A Meyyazhagan… - Journal of …, 2021 - Springer
Purpose Colorectal cancer (CRC) is one of the recurring and lethal gastrointestinal tract
disease rankings as the primary cause of worldwide morbidity and mortality. In general, the …

[HTML][HTML] The provocative roles of platelets in liver disease and cancer

PK Marie, NW Fowlkes, V Afshar-Kharghan… - Frontiers in …, 2021 - ncbi.nlm.nih.gov
Both platelets and the liver play important roles in the processes of coagulation and innate
immunity. Platelet responses at the site of an injury are rapid; their immediate activation and …

Platelet metabolism and other targeted drugs; potential impact on immunotherapy

P Kanikarla-Marie, M Lam, AV Sorokin… - Frontiers in …, 2018 - frontiersin.org
The role of platelets in cancer progression has been well recognized in the field of cancer
biology. Emerging studies are elaborating further the additional roles and added extent that …

[HTML][HTML] Unveiling antioxidant and anti-cancer potentials of characterized Annona reticulata leaf extract in 1, 2-dimethylhydrazine-induced colorectal cancer in Wistar …

N Khan, N Kumar, A Ballal, D Datta, VS Belle - Journal of Ayurveda and …, 2021 - Elsevier
Background Colorectal cancer (CC) is the third most common cancer in the world. Annona
reticulata (AR) also known as bullock's heart, is a traditional herb. AR leaf extract was …

Mean platelet volume as a possible biomarker of tumor progression in rectal cancer

M Wƚodarczyk, J Kasprzyk… - Cancer …, 2016 - content.iospress.com
BACKGROUND: Rectal cancer is a major cause of death and an early diagnosis is crucial in
decreasing mortality. Previous studies found a relation between chronic inflammation and …

[HTML][HTML] Involvement of platelet signaling pathways in colorectal cancer and new therapeutic targets

PHL Bonfitto, BAG Rodrigues… - American Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
Colorectal cancer (CRC) is one of the most widespread tumor types, and it stands as the
second leading cause of disease-related mortality globally. Due to its adverse effects, which …