This review delves into the rapidly evolving landscape of liquid biopsy technologies based
on cell-free DNA (cfDNA) and cell-free RNA (cfRNA) and their increasingly prominent role in …

A system for programmable export of RNA molecules from living cells would enable both
non-destructive monitoring of cell dynamics and engineering of cells capable of delivering …

The ability to use blood to predict the outcomes of Parkinson's disease, including disease
progression and cognitive and motor complications, would be of significant clinical value …

Emerging evidence suggests that brain derived extracellular vesicles (EVs) and particles
(EPs) can cross blood-brain barrier and mediate communication among neurons, astrocytes …

Liquid biopsies provide a means for the profiling of cell-free RNAs secreted by cells
throughout the body. Although well-annotated coding and non-coding transcripts in blood …

Long non-coding RNAs (lncRNA) play critical roles in pathogenesis of neurodegenerative
diseases. Human plasma carries lncRNAs that are stable in the blood, and their disease …

Cell-free RNA from liquid biopsies can be analyzed to determine disease tissue of origin.
We extend this concept to identify cell types of origin using the Tabula Sapiens …

Cell-free RNAs (cfRNAs) offer an opportunity to detect diseases from a transcriptomic
perspective, however, existing techniques have fallen short in generating a comprehensive …

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive
cognitive decline and memory loss. While the precise causes of AD remain unclear …

Inflammatory syndromes, including those caused by infection, are a major cause of hospital
admissions among children and are often misdiagnosed because of a lack of advanced …