Abstract The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic
Shock 2020 (J-SSCG 2020), a Japanese-specific set of clinical practice guidelines for sepsis …

Human immunoglobulin preparations for intravenous or subcutaneous administration are
the cornerstone of treatment in patients with primary immunodeficiency diseases affecting …

We have examined the effect of profound hypothermia on gut mucosal perfusion in 20
infants, aged 1.4-45 weeks, requiring cardiopulmonary bypass (CPB). After induction of …

Necrotizing Soft-Tissue Infections | New England Journal of Medicine Skip to main content
Access provided byUT MD ANDERSON CANCER CENTER The New England Journal of …

Streptococcus pyogenes, also known as group A Streptococcus (GAS), causes mild human
infections such as pharyngitis and impetigo and serious infections such as necrotizing …

Necrotizing soft tissue infections (NSTIs) rank among the more difficult disease processes
encountered by physicians and surgeons. NSTIs can arise primarily in the dermis and …

Necrotizing fasciitis (NF) is a severe, rare, potentially lethal soft tissue infection that develops
in the scrotum and perineum, the abdominal wall, or the extremities. The infection …

This review begins with a discussion of the large family of Staphylococcus aureus and beta-
hemolytic streptococcal pyrogenic toxin T lymphocyte superantigens from structural and …

Antimicrobial agents are some of the most widely, and often injudiciously, used therapeutic
drugs worldwide. Important considerations when prescribing antimicrobial therapy include …

Group A streptococci are model extracellular gram-positive pathogens responsible for
pharyngitis, impetigo, rheumatic fever, and acute glomerulonephritis. A resurgence of …