Nanoparticles (NPs) have attracted considerable attention in various fields, such as
cosmetics, the food industry, material design, and nanomedicine. In particular, the fast …

Endocytosis is a complex process whereby cell surface proteins, lipids and fluid from the
extracellular environment are packaged, sorted and internalized into cells. Endocytosis is …

Pyroptosis is a gasdermin-mediated programmed necrosis that occurs via membrane
perforation and that can be exploited for biomedical applications in cancer therapy …

Mechanical signalling affects multiple biological processes during development and in adult
organisms, including cell fate transitions, cell migration, morphogenesis and immune …

All species continuously evolve short open reading frames (sORFs) that can be templated
for protein synthesis and may provide raw materials for evolutionary adaptation. We …

Clathrin-mediated endocytosis (CME) is the major endocytic pathway in mammalian cells. It
is responsible for the uptake of transmembrane receptors and transporters, for remodeling …

The complexity of nanoscale interactions between biomaterials and cells has limited the
realization of the ultimate vision of nanotechnology in diagnostics and therapeutics. As such …

It is clear that exosomes (endosome derived vesicles) serve important roles in cellular
communication both locally and distally and that the exosomal process is abnormal in …

The lysosome has long been viewed as the recycling center of the cell. However, recent
discoveries have challenged this simple view and have established a central role of the …

Cells operate through protein interaction networks organized in space and time. Here, we
describe an approach to resolve both dimensions simultaneously by using proximity …