Periodontal therapeutics: Current host‐modulation agents and future directions

LM Golub, HM Lee - Periodontology 2000, 2020 - Wiley Online Library
With the recognition in the 1960s and 1970s of the periodontopathic importance of the
microbial biofilm and its specific anaerobic microorganisms, periodontitis was treated as an …

[HTML][HTML] Functional biomaterials for comprehensive periodontitis therapy

J Luan, R Li, W Xu, H Sun, Q Li, D Wang… - … Pharmaceutica Sinica B, 2023 - Elsevier
Periodontitis is an inflammatory disease caused by bacterial infection directly, and the
dysregulation of host immune-inflammatory response finally destroys periodontal tissues …

Matrix metalloproteinase‐8 as an inflammatory and prevention biomarker in periodontal and peri‐implant diseases

A Al-Majid, S Alassiri, N Rathnayake… - … journal of dentistry, 2018 - Wiley Online Library
Levels of and especially the degree of activation of matrix metalloproteinase (MMP‐8) in oral
fluids (ie, saliva, mouth rinse, gingival crevicular fluid (GCF) and peri‐implantitis sulcular …

Diagnostic accuracy of oral fluids biomarker profile to determine the current and future status of periodontal and peri-implant diseases

SS Gul, AA Abdulkareem, AM Sha, A Rawlinson - Diagnostics, 2020 - mdpi.com
Severe periodontitis is ranked as the sixth most prevalent disease affecting humankind, with
an estimated 740 million people affected worldwide. The diagnosis of periodontal diseases …

The effect of doxycycline-containing chitosan/carboxymethyl chitosan nanoparticles on NLRP3 inflammasome in periodontal disease

S Xu, Q Zhou, Z Jiang, Y Wang, K Yang, X Qiu… - Carbohydrate polymers, 2020 - Elsevier
A polyelectrolyte complex nanoparticle comprising chitosan (CS) and carboxymethyl
chitosan (CMCS) was prepared (CS/CMCS-NPs) by ionic gelation, which was then used as …

Tetracycline repurposing in neurodegeneration: focus on Parkinson's disease

M Bortolanza, GC Nascimento, SB Socias… - Journal of neural …, 2018 - Springer
The prevalence of Parkinson's disease, which affects millions of people worldwide, is
increasing due to the aging population. In addition to the classic motor symptoms caused by …

Regenerative surgical therapy for peri‐implantitis using deproteinized bovine bone mineral with 10% collagen, enamel matrix derivative and Doxycycline—A …

F Mercado, S Hamlet, S Ivanovski - Clinical Oral Implants …, 2018 - Wiley Online Library
Objectives There is limited evidence regarding the long‐term efficacy of regenerative
treatment for peri‐implantitis. The aim of this study was to evaluate a combination therapy of …

The effect of acknowledged and novel anti-rheumatic therapies on periodontal tissues—a narrative review

MA Martu, GA Maftei, I Luchian, OM Stefanescu… - Pharmaceuticals, 2021 - mdpi.com
Rheumatoid arthritis (RA) and periodontal disease (PD) are chronic complex inflammatory
diseases with several common susceptibility factors, especially genetic and environmental …

The neuroprotective effect of doxycycline on neurodegenerative diseases

FV Santa-Cecília, CA Leite, E Del-Bel… - Neurotoxicity …, 2019 - Springer
Neurodegenerative diseases (NDs) are a group of chronic, progressive disorders
characterized by the gradual loss of neurons that affect specific regions of the brain, which …

Local application of curcumin-loaded nanoparticles as an adjunct to scaling and root planing in periodontitis: Randomized, placebo-controlled, double-blind split …

CG Pérez-Pacheco, NAR Fernandes, FL Primo… - Clinical Oral …, 2021 - Springer
Objective Assess a single local application of curcumin-loaded nanoparticles as an adjunct
to scaling and root planing (SRP) in nonsurgical periodontal treatment (NPT). Materials and …