Chronic obstructive pulmonary disease exacerbation fundamentals: diagnosis, treatment, prevention and disease impact

M MacLeod, A Papi, M Contoli, B Beghé, BR Celli… - …, 2021 - Wiley Online Library
In chronic obstructive pulmonary disease (COPD), exacerbations (ECOPD), characterized
by an acute deterioration in respiratory symptoms, are fundamental events impacting …

[HTML][HTML] Goals of COPD treatment: Focus on symptoms and exacerbations

CF Vogelmeier, M Roman-Rodriguez, D Singh… - Respiratory …, 2020 - Elsevier
Chronic obstructive pulmonary disease (COPD) is currently a leading cause of death
worldwide, and its burden is expected to rise in the coming years. Common COPD …

Global strategy for the diagnosis, management, and prevention of chronic obstructive lung disease 2017 report. GOLD executive summary

CF Vogelmeier, GJ Criner, FJ Martinez… - American journal of …, 2017 - atsjournals.org
This Executive Summary of the Global Strategy for the Diagnosis, Management, and
Prevention of COPD, Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2017 …

History of antimicrobial drug discovery: Major classes and health impact

R Aminov - Biochemical pharmacology, 2017 - Elsevier
The introduction of antibiotics into clinical practice revolutionized the treatment and
management of infectious diseases. Before the introduction of antibiotics, these diseases …

Guidelines for the management of adult lower respiratory tract infections‐Full version

M Woodhead, F Blasi, S Ewig, J Garau… - Clinical microbiology …, 2011 - Wiley Online Library
Clin Microbiol Infect 2011; 17 (Suppl. 6): E1–E59 Abstract This document is an update of
Guidelines published in 2005 and now includes scientific publications through to May 2010 …

Airway mucus function and dysfunction

JV Fahy, BF Dickey - New England journal of medicine, 2010 - Mass Medical Soc
Pulmonary defense against environmental injury depends on airway mucus, which traps
inhaled toxins that are then cleared from the lungs by ciliary beating and cough. This review …

Azithromycin for prevention of exacerbations of COPD

RK Albert, J Connett, WC Bailey… - … England Journal of …, 2011 - Mass Medical Soc
Background Acute exacerbations adversely affect patients with chronic obstructive
pulmonary disease (COPD). Macrolide antibiotics benefit patients with a variety of …

The clinical and economic burden of chronic obstructive pulmonary disease in the USA

AJ Guarascio, SM Ray, CK Finch… - … and Outcomes Research, 2013 - Taylor & Francis
Chronic obstructive pulmonary disease (COPD) is the third most common cause of death in
the USA. In 2010, the cost of COPD in the USA was projected to be approximately US …

Acute exacerbation of COPD

FW Ko, KP Chan, DS Hui, JR Goddard, JG Shaw… - …, 2016 - Wiley Online Library
The literature of acute exacerbation of chronic obstructive pulmonary disease (COPD) is fast
expanding. This review focuses on several aspects of acute exacerbation of COPD …

Impact and prevention of severe exacerbations of COPD: a review of the evidence

DMG Halpin, M Miravitlles, N Metzdorf… - International journal of …, 2017 - Taylor & Francis
Severe exacerbations of COPD, ie, those leading to hospitalization, have profound clinical
implications for patients and significant economic consequences for society. The prevalence …