Microfluidics: Fluid physics at the nanoliter scale

TM Squires, SR Quake - Reviews of modern physics, 2005 - APS
Microfabricated integrated circuits revolutionized computation by vastly reducing the space,
labor, and time required for calculations. Microfluidic systems hold similar promise for the …

Cells on chips

J El-Ali, PK Sorger, KF Jensen - Nature, 2006 - nature.com
Microsystems create new opportunities for the spatial and temporal control of cell growth
and stimuli by combining surfaces that mimic complex biochemistries and geometries of the …

A review of microvalves

KW Oh, CH Ahn - Journal of micromechanics and …, 2006 - iopscience.iop.org
This review gives a brief overview of microvalves, and focuses on the actuation mechanisms
and their applications. One of the stumbling blocks for successful miniaturization and …

Microfabricated crossflow devices and methods

SR Quake, T Thorsen - US Patent 7,294,503, 2007 - Google Patents
(57) ABSTRACT A microfluidic device for analyzing and/or sorting biological materials (eg,
molecules such as polynucleotides and polypeptides, including proteins and enzymes; …

Integrated microfluidic devices

D Erickson, D Li - Analytica chimica acta, 2004 - Elsevier
“With the fundamentals of microscale flow and species transport well developed, the recent
trend in microfluidics has been to work towards the development of integrated devices which …

Ultrafast photonic PCR

JH Son, B Cho, SG Hong, SH Lee, O Hoxha… - Light: Science & …, 2015 - nature.com
Nucleic acid amplification and quantification via polymerase chain reaction (PCR) is one of
the most sensitive and powerful tools for clinical laboratories, precision medicine …

Blood-on-a-chip

M Toner, D Irimia - Annu. Rev. Biomed. Eng., 2005 - annualreviews.org
▪ Abstract Accurate, fast, and affordable analysis of the cellular component of blood is of
prime interest for medicine and research. Yet, most often sample preparation procedures for …

Monolithic membrane valves and diaphragm pumps for practical large-scale integration into glass microfluidic devices

WH Grover, AM Skelley, CN Liu, ET Lagally… - Sensors and Actuators B …, 2003 - Elsevier
Monolithic elastomer membrane valves and diaphragm pumps suitable for large-scale
integration into glass microfluidic analysis devices are fabricated and characterized. Valves …

PCR microfluidic devices for DNA amplification

C Zhang, J Xu, W Ma, W Zheng - Biotechnology advances, 2006 - Elsevier
The miniaturization of biological and chemical analytical devices by micro-electro-
mechanical-systems (MEMS) technology has posed a vital influence on such fields as …

[HTML][HTML] Rapid, sensitive, and quantitative detection of pathogenic DNA at the point of care via microfluidic electrochemical quantitative loop-mediated isothermal …

K Hsieh, AS Patterson, BS Ferguson… - … (International ed. in …, 2012 - ncbi.nlm.nih.gov
Abstract We present the Microfluidic Electrochemical Quantitative Loop-mediated isothermal
AMPlification (MEQ-LAMP) platform for rapid, sensitive, and quantitative detection of …