Sepsis is a leading cause of intensive care unit admission and death worldwide. Most
surviving patients show acute or chronic mental disorders, which are known as sepsis …

Tuberculous meningitis (TBM) is the most severe complication of tuberculosis (TB) and is
associated with high rates of disability and mortality. Mycobacterium tuberculosis (M. tb), the …

Background Neuroinflammation is a principal element in Alzheimer's disease (AD)
pathogenesis, so anti-inflammation may be a promising therapeutic strategy. Forsythoside B …

Background IRAK3 is a critical modulator of inflammation in innate immunity. IRAK3 is
associated with many inflammatory diseases, including sepsis, and is required in endotoxin …

Astrocytes and microglia are the main cell population besides neurons in the central
nervous system (CNS). Astrocytes support the neuronal network via maintenance of …

Background: Randomized controlled trials (RCTs) have shown uncertain clinical benefits
from perioperative intravenous glucocorticoids for perioperative neurocognitive disorders …

Influenza virus infection is a worldwide challenge that causes heavy burdens on public
health. The mortality rate of severe influenza patients is often associated with hyperactive …

Zebrafish possess the ability to regenerate dying neurons in response to retinal injury, with
both Müller glia and microglia playing integral roles in this response. Resident Müller glia …

Neuroinflammation is associated with the development of hypoactive delirium, which results
in poor clinical outcomes. Drugs effective against hypoactive sur have not yet been …

Parkinson's disease (PD) is characterized by the progressive loss of dopaminergic neurons
in the substantia nigra that primarily affects movement control. Neuroinflammation plays a …