Lymph node dissection in upper tract urothelial carcinoma: current status and future perspectives

A Dłubak, J Karwacki, K Logoń, P Tomecka… - Current Oncology …, 2023 - Springer
Abstract Purpose of Review This narrative review aims to evaluate the role of lymph node
dissection (LND) in upper tract urothelial carcinoma (UTUC) and its implications for staging …

Age-associated differences in the human lung extracellular matrix

MLK Ngassie, M De Vries, T Borghuis… - … of Physiology-Lung …, 2023 - journals.physiology.org
Extracellular matrix (ECM) remodeling has been associated with chronic lung diseases.
However, information about specific age-associated differences in lung ECM is currently …

Candesartan prevents arteriopathy progression in cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy model

T Kato, R Manabe, H Igarashi… - The Journal of …, 2021 - Am Soc Clin Investig
Cerebral small vessel disease (CSVD) causes dementia and gait disturbance due to
arteriopathy. Cerebral autosomal recessive arteriopathy with subcortical infarcts and …

LncRNA HCP5 acts as a miR-128-3p sponge to promote the progression of multiple myeloma through activating Wnt/β‐catenin/cyclin D1 signaling via PLAGL2

Q Liu, R Ran, M Song, X Li, Z Wu, G Dai… - Cell Biology and …, 2022 - Springer
Background Although long non-coding RNA (lncRNA) HCP plays essential roles in human
cancers, its function and mechanism in multiple myeloma (MM) have not crystallized …

Fibulin 2 is hypermethylated and suppresses tumor cell proliferation through inhibition of cell adhesion and extracellular matrix genes in non-small cell lung cancer

Y Ma, M Nenkov, DC Schröder, M Abubrig… - International journal of …, 2021 - mdpi.com
Fibulins (FBLNs), interacting with cell adhesion receptors and extracellular matrix (ECM)
components, play multiple roles in ECM structures and tissue functions. Abnormal …

ITGBL1 promotes anoikis resistance and metastasis in human gastric cancer via the AKT/FBLN2 axis

K Shen, W Xia, K Wang, J Li, W Xu… - Journal of Cellular …, 2024 - Wiley Online Library
The resistance to anoikis plays a critical role in the metastatic progression of various types of
malignancies, including gastric cancer (GC). Nevertheless, the precise mechanism behind …

Comparison of lesional juvenile myositis and lupus skin reveals overlapping yet unique disease pathophysiology

JL Turnier, LM Pachman, L Lowe, LC Tsoi… - Arthritis & …, 2021 - Wiley Online Library
Objective Skin inflammation heralds systemic disease in juvenile myositis, yet we lack an
understanding of pathogenic mechanisms driving skin inflammation in this disease. We …

FBLN2 is associated with basal cell markers Krt14 and ITGB1 in mouse mammary epithelial cells and has a preferential expression in molecular subtypes of human …

AA WalyEldeen, S Sabet, SE Anis, T Stein… - Breast Cancer Research …, 2024 - Springer
Abstract Background Fibulin-2 (FBLN2) is a secreted extracellular matrix (ECM) glycoprotein
and has been identified in the mouse mammary gland, in cap cells of terminal end buds …

SFRP1 expression is inversely Associated with Metastasis formation in Canine Mammary Tumours

J Seitz, A Bilsland, C Puget, I Baasner… - Journal of Mammary …, 2023 - Springer
Abstract Background Canine mammary tumours (CMTs) are the most frequent tumours in
intact female dogs and show strong similarities with human breast cancer. In contrast to the …

Targeted O-glycoproteomics for the development of diagnostic markers for advanced colorectal cancer

D Takakura, S Ohashi, N Kobayashi, M Tokuhisa… - Frontiers in …, 2023 - frontiersin.org
Aberrant glycosylation is a prominent feature of cancer, that can be used as targets to
improve the existing cancer biomarkers, and help to assess metastasis risks, and …