Gene body methylation in cancer: molecular mechanisms and clinical applications

Q Wang, F Xiong, G Wu, W Liu, J Chen, B Wang… - Clinical …, 2022 - Springer
DNA methylation is an important epigenetic mechanism that regulates gene expression. To
date, most DNA methylation studies have focussed on CpG islands in the gene promoter …

Molecular mechanisms of phenotypic plasticity in social insects

M Corona, R Libbrecht, DE Wheeler - Current opinion in insect science, 2016 - Elsevier
Highlights•The IIS is the core pathway underlying caste determination.•The pathway can be
regulated by genes, nutrition, and other pathways.•Epigenetics mechanisms have been …

Genomic signatures of evolutionary transitions from solitary to group living

KM Kapheim, H Pan, C Li, SL Salzberg, D Puiu… - Science, 2015 - science.org
The evolution of eusociality is one of the major transitions in evolution, but the underlying
genomic changes are unknown. We compared the genomes of 10 bee species that vary in …

Molecular signatures of plastic phenotypes in two eusocial insect species with simple societies

S Patalano, A Vlasova, C Wyatt… - Proceedings of the …, 2015 - National Acad Sciences
Phenotypic plasticity is important in adaptation and shapes the evolution of organisms.
However, we understand little about what aspects of the genome are important in facilitating …

DNA methylation and histone H1 jointly repress transposable elements and aberrant intragenic transcripts

J Choi, DB Lyons, MY Kim, JD Moore, D Zilberman - Molecular Cell, 2020 - cell.com
DNA methylation and histone H1 mediate transcriptional silencing of genes and
transposable elements, but how they interact is unclear. In plants and animals with mosaic …

DNMT1 mutant ants develop normally but have disrupted oogenesis

I Ivasyk, L Olivos-Cisneros, S Valdés-Rodríguez… - Nature …, 2023 - nature.com
Although DNA methylation is an important gene regulatory mechanism in mammals, its
function in arthropods remains poorly understood. Studies in eusocial insects have argued …

An evolutionary case for functional gene body methylation in plants and animals

D Zilberman - Genome biology, 2017 - Springer
An evolutionary case for functional gene body methylation in plants and animals | Genome
Biology Skip to main content SpringerLink Account Menu Find a journal Publish with us Track …

Evolutionary conservation of the eumetazoan gene regulatory landscape

M Schwaiger, A Schönauer, AF Rendeiro… - Genome …, 2014 - genome.cshlp.org
Despite considerable differences in morphology and complexity of body plans among
animals, a great part of the gene set is shared among Bilateria and their basally branching …

Function and Evolution of DNA Methylation in Nasonia vitripennis

X Wang, D Wheeler, A Avery, A Rago, JH Choi… - PLoS …, 2013 - journals.plos.org
The parasitoid wasp Nasonia vitripennis is an emerging genetic model for functional
analysis of DNA methylation. Here, we characterize genome-wide methylation at a base-pair …

DNA methylation in social insects: how epigenetics can control behavior and longevity

H Yan, R Bonasio, DF Simola, J Liebig… - Annual Review of …, 2015 - annualreviews.org
In eusocial insects, genetically identical individuals can exhibit striking differences in
behavior and longevity. The molecular basis of such phenotypic plasticity is of great interest …