Cardiovascular disease remains a leading cause of both morbidity and mortality worldwide.
It is widely accepted that both concomitant medications (drug–drug interactions, DDIs) and …

Purpose To determine risk factors for each severity-based category of potential drug-drug
interactions (DDIs) encountered at intensive care unit (ICU) patients. Methods This was a …

Background: Concomitant use of several drugs for a patient is often imposing increased risk
of drug–drug interactions. Drug–drug interactions are a major cause for concern in patients …

The ever-increasing cost of drug discovery and development represents a significant
challenge for the pharmaceutical industry and new strategies to bridge studies between …

Background Elderly people are most commonly associated with cardiac disease.
Cardiovascular diseases are interlinked with co-morbidities which require multiple drug …

Objective: Cardiovascular disease (CVD) drugs have been frequently implicated in adverse
drug reaction (ADR)-related hospitalizations. Drug–drug interactions (DDIs) are common …

Background The treatment of heart failure patients is very complex and includes lifestyle
modification as well as different pharmacological therapies. Polypharmacy is very common …

Background Chronic kidney disease (CKD) alters the pharmacokinetic and
pharmacodynamic responses of various renally excreted drugs and increases the risk of …

Background Drug-related problems are associated with high mortality, complications,
prolonged hospital stay, compromised quality of life, and increased healthcare costs. This …

Background Pneumonia patients are usually hospitalized due to severe nature of the
disease or for the management of comorbid illnesses or associated symptoms. Such …