[HTML][HTML] Epidemiology, virulence factors and management of the pneumococcus

C Feldman, R Anderson - F1000Research, 2016 - ncbi.nlm.nih.gov
Pneumococcal infections continue to cause significant morbidity and mortality in patients
throughout the world. This microorganism remains the most common bacterial cause of …

Deacetylation of sialic acid by esterases potentiates pneumococcal neuraminidase activity for mucin utilization, colonization and virulence

HF Kahya, PW Andrew, H Yesilkaya - PLoS pathogens, 2017 - journals.plos.org
Pneumococcal neuraminidase is a key enzyme for sequential deglycosylation of host
glycans, and plays an important role in host survival, colonization, and pathogenesis of …

Rgg-Shp regulators are important for pneumococcal colonization and invasion through their effect on mannose utilization and capsule synthesis

X Zhi, IT Abdullah, O Gazioglu, I Manzoor, S Shafeeq… - Scientific Reports, 2018 - nature.com
Microbes communicate with each other by using quorum sensing (QS) systems and
modulate their collective 'behavior'for in-host colonization and virulence, biofilm formation …

The pneumococcal surface proteins PspA and PspC sequester host C4-binding protein to inactivate complement C4b on the bacterial surface

KS Haleem, YM Ali, H Yesilkaya, T Kohler… - Infection and …, 2019 - Am Soc Microbiol
Complement is a critical component of antimicrobial immunity. Various complement
regulatory proteins prevent host cells from being attacked. Many pathogens have acquired …

Time-resolved RNA-seq analysis to unravel the in vivo competence induction by Streptococcus pneumoniae during pneumonia-derived sepsis

MW Oh, J Lin, SY Chong, SQ Lew, T Alam… - Microbiology …, 2024 - Am Soc Microbiol
Competence development in Streptococcus pneumoniae (pneumococcus) is tightly
intertwined with virulence. In addition to genes encoding genetic transformation machinery …

The Eukaryote-Like Serine/Threonine Kinase STK Regulates the Growth and Metabolism of Zoonotic Streptococcus suis

C Zhang, W Sun, M Tan, M Dong, W Liu… - Frontiers in cellular …, 2017 - frontiersin.org
Like eukaryotes, bacteria express one or more serine/threonine kinases (STKs) that initiate
diverse signaling networks. The STK from Streptococcus suis is encoded by a single-copy …

[HTML][HTML] In vitro and in vivo characterisation of Listeria monocytogenes outbreak isolates

AC Stratakos, UZ Ijaz, P Ward, M Linton, C Kelly… - Food Control, 2020 - Elsevier
Listeriosis is an important food-borne disease responsible for high rates of morbidity and
mortality. L. monocytogenes has been the cause of several foodborne outbreaks and its …

Interaction of Neisseria meningitidis carrier and disease isolates of MenB cc32 and MenW cc22 with epithelial cells of the nasopharyngeal barrier

S Peters, K Mohort, H Claus, C Stigloher… - Frontiers in Cellular …, 2024 - frontiersin.org
Neisseria meningitidis (Nm, the meningococcus) is considered an asymptomatic colonizer of
the upper respiratory tract and a transient member of its microbiome. It is assumed that the …

Host-glycan metabolism is regulated by a species-conserved two-component system in Streptococcus pneumoniae

PR Andreassen, C Trappetti, V Minhas… - PLoS …, 2020 - journals.plos.org
Pathogens of the Streptococcus genus inhabit many different environmental niches during
the course of an infection in a human host and the bacteria must adjust their metabolism …

Activation of invariant natural killer T cells stimulated with microbial α-mannosyl glycolipids

M Shimamura, M Yamamura, T Nabeshima, N Kitano… - Scientific reports, 2017 - nature.com
Some synthetic and bacterial glycolipids presented by CD1d specifically activate invariant
NKT (iNKT) cells bearing an invariant Vα14-Jα18 (mouse) or Vα24-Jα18 (human) TCR. The …