As the population ages due to demographic trends and gains in life expectancy, the
incidence and prevalence of dementia increases, and the need to understand the etiology …

Although a causal association remains to be determined, epidemiologic evidence suggests
an association between hearing loss and increased risk of dementia. If we determine the …

Alzheimer's disease (AD) pathologies were discovered in the accessible neurosensory
retina. However, their exact nature and topographical distribution, particularly in the early …

The retina is an emerging CNS target for potential noninvasive diagnosis and tracking of
Alzheimer's disease (AD). Studies have identified the pathological hallmarks of AD …

In the last 20 years, research focused on developing retinal imaging as a source of potential
biomarkers for Alzheimer's disease and other neurodegenerative diseases, has increased …

Alzheimer's Disease (AD) is a devastating neurodegenerative disorder of the brain, clinically
characterised by cognitive deficits that gradually worsen over time. There is, at present, no …

Pericyte loss and deficient vascular platelet-derived growth factor receptor-β (PDGFRβ)
signaling are prominent features of the blood–brain barrier breakdown described in …

Introduction Retinal characteristics are increasingly recognized as biomarkers for
neurodegenerative diseases. Retinal thickness measured by optical coherence tomography …

Background Alzheimer's disease (AD) pathology begins several years before the clinical
onset. The long preclinical phase is composed of three stages according to the …

The neurosensory retina emerges as a prominent site of Alzheimer's disease (AD)
pathology. As a CNS extension of the brain, the neuro retina is easily accessible for …