MT1-MMP as a key regulator of metastasis

N Tanaka, T Sakamoto - Cells, 2023 - mdpi.com
Membrane type1-matrix metalloproteinase (MT1-MMP) is a member of metalloproteinases
that is tethered to the transmembrane. Its major function in cancer progression is to directly …

[HTML][HTML] Cytoskeletal crosstalk: A focus on intermediate filaments

L Pradeau-Phélut, S Etienne-Manneville - Current Opinion in Cell Biology, 2024 - Elsevier
The cytoskeleton, comprising actin microfilaments, microtubules, and intermediate filaments,
is crucial for cell motility and tissue integrity. While prior studies largely focused on individual …

The prognostic and therapeutic potential of vimentin in colorectal cancer

Z Kalaei, AA Shekarchi, M Hojjat-Farsangi… - Molecular Biology …, 2024 - Springer
Several cells and molecules in the tumor microenvironment have been introduced as
effective factors in the prognosis and progression of colorectal cancer. As a key element of …

Vimentin promotes collective cell migration through collagen networks via increased matrix remodeling and spheroid fluidity

MT Ho Thanh, A Poudel, S Ameen, R Carroll, M Wu… - bioRxiv, 2024 - biorxiv.org
The intermediate filament (IF) protein vimentin is associated with many diseases with
phenotypes of enhanced cellular migration and aggressive invasion through the …