[HTML][HTML] Brain default-mode network dysfunction in addiction

R Zhang, ND Volkow - Neuroimage, 2019 - Elsevier
Aberrant patterns of brain functional connectivity in the default mode network (DMN) have
been observed across different classes of substance use disorder (SUD) and are associated …

Sex/gender differences in the time-course for the development of substance use disorder: a focus on the telescoping effect

EB Towers, IL Williams, EI Qillawala, EF Rissman… - Pharmacological …, 2023 - Elsevier
Sex/gender effects have been demonstrated for multiple aspects of addiction, with one of the
most commonly cited examples being the “telescoping effect” where women meet criteria …

Assessing synaptic density in Alzheimer disease with synaptic vesicle glycoprotein 2A positron emission tomographic imaging

MK Chen, AP Mecca, M Naganawa, SJ Finnema… - JAMA …, 2018 - jamanetwork.com
Importance Synaptic loss is well established as the major structural correlate of cognitive
impairment in Alzheimer disease (AD). The ability to measure synaptic density in vivo could …

The effects of Δ9-tetrahydrocannabinol on the dopamine system

MAP Bloomfield, AH Ashok, ND Volkow, OD Howes - Nature, 2016 - nature.com
The effects of Δ9-tetrahydrocannabinol (THC), the main psychoactive ingredient in cannabis,
are a pressing concern for global mental health. Patterns of cannabis use are changing …

Cannabis addiction and the brain: a review

A Zehra, J Burns, CK Liu, P Manza, CE Wiers… - Journal of Neuroimmune …, 2018 - Springer
Cannabis is the most commonly used substance of abuse in the United States after alcohol
and tobacco. With a recent increase in the rates of cannabis use disorder (CUD) and a …

Sex-dependent effects of cannabis and cannabinoids: a translational perspective

ZD Cooper, RM Craft - Neuropsychopharmacology, 2018 - nature.com
Recent policy changes have led to significant increases in the use of cannabis for both
medical and recreational purposes. Although men are more likely to endorse past month …

[HTML][HTML] The neuropsychopharmacology of cannabis: A review of human imaging studies

MAP Bloomfield, C Hindocha, SF Green… - Pharmacology & …, 2019 - Elsevier
The laws governing cannabis are evolving worldwide and associated with changing
patterns of use. The main psychoactive drug in cannabis is Δ 9-tetrahydrocannabinol (THC) …

Comparison of [11C]UCB-J and [18F]FDG PET in Alzheimer's disease: A tracer kinetic modeling study

MK Chen, AP Mecca, M Naganawa… - Journal of Cerebral …, 2021 - journals.sagepub.com
[11C] UCB-J PET for synaptic vesicle glycoprotein 2 A (SV2A) has been proposed as a
suitable marker for synaptic density in Alzheimer's disease (AD). We compared [11C] UCB-J …

Antidepressant-like and anxiolytic-like effects of cannabidiol: a chemical compound of Cannabis sativa

AR de Mello Schier… - CNS & Neurological …, 2014 - ingentaconnect.com
Anxiety and depression are pathologies that affect human beings in many aspects of life,
including social life, productivity and health. Cannabidiol (CBD) is a constituent non …

Mechanisms underlying sex differences in cannabis use

KC Calakos, S Bhatt, DW Foster, KP Cosgrove - Current addiction reports, 2017 - Springer
Abstract Purpose of the Review Cannabis is the most commonly used illicit substance
worldwide. In recent decades, highly concentrated products have flooded the market, and …