Progress in infrared spectroscopy as an efficient tool for predicting protein secondary structure

S Yang, Q Zhang, H Yang, H Shi, A Dong… - International Journal of …, 2022 - Elsevier
Infrared (IR) spectroscopy is a highly sensitive technique that provides complete information
on chemical compositions. The IR spectra of proteins or peptides give rise to nine …

Advances in mid-infrared spectroscopy for chemical analysis

J Haas, B Mizaikoff - Annual Review of Analytical Chemistry, 2016 - annualreviews.org
Infrared spectroscopy in the 3–20 μm spectral window has evolved from a routine laboratory
technique into a state-of-the-art spectroscopy and sensing tool by benefitting from recent …

[HTML][HTML] Quantum cascade lasers (QCLs) in biomedical spectroscopy

A Schwaighofer, M Brandstetter, B Lendl - Chemical Society Reviews, 2017 - pubs.rsc.org
Quantum cascade lasers (QCL) are the first room temperature semiconductor laser source
for the mid-IR spectral region, triggering substantial development for the advancement of …

Recent advances in flow injection analysis

M Trojanowicz, K Kołacińska - Analyst, 2016 - pubs.rsc.org
A dynamic development of methodologies of analytical flow injection measurements during
four decades since their invention has reinforced the solid position of flow analysis in the …

The next generation of IR spectroscopy: EC-QCL-based mid-IR transmission spectroscopy of proteins with balanced detection

CK Akhgar, G Ramer, M Żbik, A Trajnerowicz… - Analytical …, 2020 - ACS Publications
We report a mid-IR transmission setup for the analysis of the protein amide I and amide II
band in aqueous solutions that achieves a limit of detection as low as 0.0025 mg mL–1 …

Mid-infrared spectroscopy for protein analysis: potential and challenges

ÁI López-Lorente, B Mizaikoff - Analytical and bioanalytical chemistry, 2016 - Springer
Mid-infrared (MIR) spectroscopy investigates the interaction of MIR photons with both
organic and inorganic molecules via the excitation of vibrational and rotational modes …

Infrared spectroscopic imaging advances as an analytical technology for biomedical sciences

TP Wrobel, R Bhargava - Analytical chemistry, 2018 - ACS Publications
Optical chemical imaging seeks to nondestructively acquire spatially resolved chemical
information without the use of labels or probes. The combination of vibrational mid-infrared …

Beyond Fourier Transform Infrared Spectroscopy: External cavity quantum cascade laser-based mid-infrared transmission spectroscopy of proteins in the Amide I and …

A Schwaighofer, M Montemurro, S Freitag… - Analytical …, 2018 - ACS Publications
In this work, we present a setup for mid-IR measurements of the protein amide I and amide II
bands in aqueous solution. Employing a latest generation external cavity-quantum cascade …

[HTML][HTML] Broadband laser-based mid-infrared spectroscopy employing a quantum cascade detector for milk protein analysis

A Dabrowska, M David, S Freitag, AM Andrews… - Sensors and Actuators B …, 2022 - Elsevier
Mid-infrared chemical sensors based on quantum cascade technology offer a number of
properties surpassing conventional spectrometric techniques. In this work, we combine a …

QCL–IR spectroscopy for in-line monitoring of proteins from preparative ion-exchange chromatography

CK Akhgar, J Ebner, O Spadiut… - Analytical …, 2022 - ACS Publications
In this study, an external cavity-quantum cascade laser-based mid-infrared (IR) spectrometer
was applied for in-line monitoring of proteins from preparative ion-exchange …