Background The gastrointestinal peptide hormone ghrelin was discovered in 1999 as the
endogenous ligand of the growth hormone secretagogue receptor. Increasing evidence …

Small synthetic molecules called growth hormone secretagogues (GHSs) stimulate the
release of growth hormone (GH) from the pituitary. They act through the GHS-R, a G protein …

Feeding behavior is often separated into homeostatic and hedonic components. Hedonic
feeding, which can be triggered by visual or olfactory food cues, involves brain regions that …

Alzheimer's disease and other related neurodegenerative diseases are highly debilitating
disorders that affect millions of people worldwide. Efforts towards developing effective …

Ghrelin is brain-gut peptide with growth hormone-releasing and appetite-inducing activities.
It is mainly secreted from the stomach mucosa but it is also expressed widely in different …

Recent progress in the field of energy homeostasis was triggered by the discovery of
adipocyte hormone leptin and revealed a complex regulatory neuroendocrine network. A …

Brain‐derived neurotrophic factor (BDNF) has been shown to mediate the effects of exercise
on synaptic plasticity and cognitive function, in a process in which energy metabolism …

Ghrelin, a peptide hormone predominantly produced by the stomach, was isolated as the
endogenous ligand for the growth hormone secretagogue receptor. Ghrelin is a potent …

Background/Aims: The gastric peptide ghrelin, an endogenous ligand for growth-hormone
secretagogue receptor, has two major molecular forms: acylated ghrelin and desacyl …

Ghrelin is the only known peripherally-derived orexigenic hormone, increasing appetite and
subsequent food intake. The ghrelinergic system has therefore received considerable …