Protecting the kidney in systemic lupus erythematosus: from diagnosis to therapy

NI Maria, A Davidson - Nature Reviews Rheumatology, 2020 - nature.com
Lupus nephritis (LN) is a common manifestation of systemic lupus erythematosus that can
lead to irreversible renal impairment. Although the prognosis of LN has improved …

New biomarkers in SLE: from bench to bedside

R Capecchi, I Puxeddu, F Pratesi, P Migliorini - Rheumatology, 2020 - academic.oup.com
Biomarkers may have a diagnostic or monitoring value, or may predict response to therapy
or disease course. The aim of this review is to discuss new serum and urinary biomarkers …

Lupus nephritis: challenges and progress

A Davidson, C Aranow, M Mackay - Current Opinion in …, 2019 - journals.lww.com
The collaborative efforts of patients, clinical and translational researchers, the
pharmaceutical industry and funding sources are needed to advance therapies for lupus …

Smartphone-based tape sensors for multiplexed rapid urinalysis

X He, Q Pei, T Xu, X Zhang - Sensors and Actuators B: Chemical, 2020 - Elsevier
Recent advances in biofluids monitoring have positioned urine as a non-invasive candidate
for clinical diagnosis. In this paper, we employ adhesive tapes with indicator-functionalized …

V‐Set Immunoglobulin Domain–Containing Protein 4 as a Novel Serum Biomarker of Lupus Nephritis and Renal Pathology Activity

C Tang, S Zhang, A Teymur, B Yang… - Arthritis & …, 2023 - Wiley Online Library
Objective To discover novel serum biomarkers that have diagnostic or predictive value in
lupus nephritis (LN). Methods Using a quantitative protein microarray, we screened for high …

Proteomic analysis of laser captured tubular tissues reveals complement activation and mitochondrial dysfunction in autoimmune related kidney diseases

M Xiao, X Chi, X Zhu, Z Xu, Y Zou, Y Peng, S Luan… - Scientific Reports, 2024 - nature.com
Autoimmune related kidney diseases (ARKDs), including minimal change nephropathy
(MCN), membranous nephropathy (MN), IgA nephropathy (IgAN), and lupus nephritis (LN) …

The urinary proteome infers dysregulation of mitochondrial, lysosomal, and protein reabsorption processes in chronic kidney disease of unknown etiology (CKDu)

RT Kolli, SC Gunasekara, MW Foster… - American Journal …, 2023 - journals.physiology.org
Chronic kidney disease (CKD) of uncertain etiology (CKDu) is a global health concern
affecting tropical farming communities. CKDu is not associated with typical risk factors (eg …

Advances in proteomic profiling of pediatric kidney diseases

TD Cummins, EA Korte, S Bhayana, ML Merchant… - Pediatric …, 2022 - Springer
Chronic kidney disease (CKD) can progress to kidney failure and require dialysis or
transplantation, while early diagnosis can alter the course of disease and lead to better …

AFM negatively regulates the infiltration of monocytes to mediate sepsis-associated acute kidney injury

C Guo, Y Fan, J Cheng, Y Deng, X Zhang… - Frontiers in …, 2023 - frontiersin.org
Background Sepsis is organ dysfunction due to the host's deleterious response to infection,
and the kidneys are one of the organs damaged in common sepsis. Sepsis-associated acute …

Recent advances of proteomics in management of acute kidney injury

I Pejchinovski, S Turkkan, M Pejchinovski - Diagnostics, 2023 - mdpi.com
Acute Kidney Injury (AKI) is currently recognized as a life-threatening disease, leading to an
exponential increase in morbidity and mortality worldwide. At present, AKI is characterized …