Etiology, evaluation, and management of xerostomia

JW Millsop, EA Wang, N Fazel - Clinics in dermatology, 2017 - Elsevier
Xerostomia is defined as the complaint of oral dryness. It is a condition that primarily affects
older adults and can have a significant negative effect on one's quality of life. Patients with …

Clinical management of salivary gland hypofunction and xerostomia in head-and-neck cancer patients: successes and barriers

A Vissink, JB Mitchell, BJ Baum, KH Limesand… - International Journal of …, 2010 - Elsevier
The most significant long-term complication of radiotherapy in the head-and-neck region is
hyposalivation and its related complaints, particularily xerostomia. This review addresses …

Salivary gland hypofunction and xerostomia in head and neck radiation patients

SB Jensen, A Vissink, KH Limesand… - JNCI …, 2019 - academic.oup.com
Background The most manifest long-term consequences of radiation therapy in the head
and neck cancer patient are salivary gland hypofunction and a sensation of oral dryness …

Dry mouth: a critical topic for older adult patients

P Han, P Suarez-Durall, R Mulligan - Journal of prosthodontic …, 2015 - jstage.jst.go.jp
Purpose: Diminished salivary flow, or dry mouth impacts the oral health of many older adults,
dentate and edentulous. As a result typical oral conditions can prove more challenging to …

Salivary hypofunction: an update on aetiology, diagnosis and therapeutics

J Saleh, MAZ Figueiredo, K Cherubini, FG Salum - Archives of oral biology, 2015 - Elsevier
Saliva is of paramount importance for the maintenance of oral and general homeostasis.
Salivary hypofunction predispose patients to disorders such as dysgeusia, pain and burning …

Current management of xerostomia in head and neck cancer patients

CAO Nathan, AA Asarkar, P Entezami, J Corry… - American Journal of …, 2023 - Elsevier
Radiotherapy (RT) continues to play a key role in the management of head and neck cancer
(HNC). Xerostomia remains a principal detriment to the quality of life (QoL) for 80% of …

Radiotherapy induced xerostomia: Mechanisms, diagnostics, prevention and treatment–Evidence based up to 2013

J Kałużny, M Wierzbicka, H Nogala, P Milecki… - Otolaryngologia …, 2014 - Elsevier
Definition and prevalence of xerostomia were shortly presented. Radiosensitivity of the
salivary glands, mechanism, diagnostics, and possible prediction methods of the intensity of …

Radiotherapy-induced salivary dysfunction: Structural changes, pathogenetic mechanisms and therapies

MD Acauan, MAZ Figueiredo, K Cherubini… - Archives of Oral …, 2015 - Elsevier
Purpose This review addressed the structural changes observed in salivary glands and
pathogenic mechanisms resulting from oxidative stress caused by radiotherapy. The …

Cost-effectiveness landscape analysis of treatments addressing xerostomia in patients receiving head and neck radiation therapy

LS Sasportas, AT Hosford, MA Sodini, DJ Waters… - Oral surgery, oral …, 2013 - Elsevier
Head and neck (H&N) radiation therapy (RT) can induce irreversible damage to the salivary
glands thereby causing long-term xerostomia or dry mouth in 68%-85% of the patients. Not …

Xerostomia in head and neck malignancy

SR Porter, S Fedele, KM Habbab - Oral oncology, 2010 - Elsevier
Xerostomia (dry mouth) as a consequence of treatment of head and neck malignancy is
almost always due to radiotherapy. The resultant salivary gland dysfunction can adversely …