The double life of group B Streptococcus: asymptomatic colonizer and potent pathogen

B Armistead, E Oler, KA Waldorf, L Rajagopal - Journal of molecular biology, 2019 - Elsevier
Group B streptococcus (GBS) is a β-hemolytic gram-positive bacterium that colonizes the
lower genital tract of approximately 18% of women globally as an asymptomatic member of …

Bacterial capsules: Occurrence, mechanism, and function

S Gao, W Jin, Y Quan, Y Li, Y Shen, S Yuan… - npj Biofilms and …, 2024 - nature.com
In environments characterized by extended multi-stress conditions, pathogens develop a
variety of immune escape mechanisms to enhance their ability to infect the host. The …

A current review of pathogenicity determinants of Streptococcus sp.

PS Lannes‐Costa, JSS De Oliveira… - Journal of Applied …, 2021 - academic.oup.com
The genus Streptococcus comprises important pathogens, many of them are part of the
human or animal microbiota. Advances in molecular genetics, taxonomic approaches and …

Bacterial and host determinants of group B streptococcal infection of the neonate and infant

A Furuta, A Brokaw, G Manuel, M Dacanay… - Frontiers in …, 2022 - frontiersin.org
Group B streptococci (GBS) are Gram-positive β-hemolytic bacteria that can cause serious
and life-threatening infections in neonates manifesting as sepsis, pneumonia, meningitis …

CRISPR contributes to adhesion, invasion, and biofilm formation in Streptococcus agalactiae by repressing capsular polysaccharide production

M Nie, Y Dong, Q Cao, D Zhao, S Ji… - Microbiology …, 2022 - Am Soc Microbiol
The clustered regularly interspaced palindromic repeat (CRISPR)-associated (Cas) system
functions classically as a prokaryotic defense system against invading mobile genetic …

Virulence factors of meningitis-causing bacteria: enabling brain entry across the blood–brain barrier

R Herold, H Schroten, C Schwerk - International journal of molecular …, 2019 - mdpi.com
Infections of the central nervous system (CNS) are still a major cause of morbidity and
mortality worldwide. Traversal of the barriers protecting the brain by pathogens is a …

The CovR regulatory network drives the evolution of Group B Streptococcus virulence

MV Mazzuoli, M Daunesse, H Varet… - PLoS …, 2021 - journals.plos.org
Virulence of the neonatal pathogen Group B Streptococcus is under the control of the master
regulator CovR. Inactivation of CovR is associated with large-scale transcriptome …

Analysis of Susceptibility to the Antimicrobial and Anti-Biofilm Activity of Human Milk Lactoferrin in Clinical Strains of Streptococcus agalactiae With Diverse Capsular …

J Lu, MA Guevara, JD Francis, SK Spicer… - Frontiers in Cellular …, 2021 - frontiersin.org
Group B Streptococcus (GBS) is one of the leading infection-related causes of adverse
maternal and neonatal outcomes. This includes chorioamnionitis, which leads to preterm …

Group B Streptococcus cpsE Is Required for Serotype V Capsule Production and Aids in Biofilm Formation and Ascending Infection of the Reproductive Tract during …

K Noble, J Lu, MA Guevara, RS Doster… - ACS infectious …, 2021 - ACS Publications
Group B Streptococcus (GBS) is an encapsulated Gram-positive pathogen that causes
ascending infections of the reproductive tract during pregnancy. The capsule of this …

A Mobile Genetic Element Promotes the Association Between Serotype M28 Group A Streptococcus Isolates and Cases of Puerperal Sepsis

I Jain, P Sarkar, JL Danger, J Medicielo… - The Journal of …, 2019 - academic.oup.com
Background Bacterial infections following childbirth—so-called puerperal infections—cause
morbidity in 5%–10% of all new mothers. At low frequency, the infection can spread to the …