Polymer degradation and drug delivery in PLGA‐based drug–polymer applications: A review of experiments and theories

Y Xu, CS Kim, DM Saylor, D Koo - Journal of biomedical …, 2017 - Wiley Online Library
Poly (lactic‐co‐glycolic acid)(PLGA) copolymers have been broadly used in controlled drug
release applications. Because these polymers are biodegradable, they provide an attractive …

Electrospraying of polymers with therapeutic molecules: State of the art

N Bock, TR Dargaville, MA Woodruff - Progress in polymer science, 2012 - Elsevier
The encapsulation and release of bioactive molecules from polymeric vehicles represents
the holy grail of drug and growth factor delivery therapies, whereby sustained and controlled …

Advances in nanotechnology and nanomaterials based strategies for neural tissue engineering

R Kumar, KR Aadil, S Ranjan, VB Kumar - Journal of Drug Delivery Science …, 2020 - Elsevier
Recent development in science and technology and invention of wonderful nanomaterials
by nanotechnology helps advances in healthcare and treatment. Nerve degeneration, scar …

A review on mechanical considerations for chronically-implanted neural probes

A Lecomte, E Descamps… - Journal of neural …, 2018 - iopscience.iop.org
This review intends to present a comprehensive analysis of the mechanical considerations
for chronically-implanted neural probes. Failure of neural electrical recordings or stimulation …

Recent trends in stabilising peptides and proteins in pharmaceutical formulation–considerations in the choice of excipients

L Jorgensen, S Hostrup, EH Moeller… - Expert opinion on drug …, 2009 - Taylor & Francis
In the area of peptide and protein pharmaceuticals, both the physical and chemical stability
of biopharmaceuticals are critical and need to be optimised when formulating a drug …

Nanotechnological strategies for nerve growth factor delivery: Therapeutic implications in Alzheimer's disease

C Faustino, P Rijo, CP Reis - Pharmacological research, 2017 - Elsevier
Alzheimer's disease (AD) is a progressive neurodegenerative disorder associated with
amyloid-β peptide misfolding and aggregation. Neurotrophic factors, such as nerve growth …

Periurethral injection of autologous adipose-derived stem cells with controlled-release nerve growth factor for the treatment of stress urinary incontinence in a rat …

W Zhao, C Zhang, C Jin, Z Zhang, D Kong, W Xu, Y Xiu - European urology, 2011 - Elsevier
BACKGROUND: Stem cell therapy is a promising therapeutic strategy for stress urinary
incontinence (SUI). However, its current efficacy is insufficient. OBJECTIVE: We designed a …

Polycaprolactone and bovine serum albumin based nanofibers for controlled release of nerve growth factor

CM Valmikinathan, S Defroda, X Yu - Biomacromolecules, 2009 - ACS Publications
Tissue engineering approaches for peripheral nerve regeneration employ biodegradable
scaffolds coupled with growth factors for improved performance in regeneration of large …

Incorporating platelet-rich plasma into electrospun scaffolds for tissue engineering applications

SA Sell, PS Wolfe, JJ Ericksen, DG Simpson… - … Engineering Part A, 2011 - liebertpub.com
Platelet-rich plasma (PRP) therapy has seen a recent spike in clinical interest due to the
potential that the highly concentrated platelet solutions hold for stimulating tissue repair and …

Scaffolds for growth factor delivery as applied to bone tissue engineering

KA Blackwood, N Bock, TR Dargaville… - … Journal of Polymer …, 2012 - Wiley Online Library
There remains a substantial shortfall in the treatment of severe skeletal injuries. The current
gold standard of autologous bone grafting from the same patient has many undesirable side …