Pathogenesis of Helicobacter pylori Infection

JG Kusters, AHM Van Vliet… - Clinical microbiology …, 2006 - Am Soc Microbiol
Helicobacter pylori is the first formally recognized bacterial carcinogen and is one of the
most successful human pathogens, as over half of the world's population is colonized with …

Helicobacter pylori and gastrointestinal tract adenocarcinomas

RM Peek Jr, MJ Blaser - Nature Reviews Cancer, 2002 - nature.com
Although gastric adenocarcinoma is associated with the presence of Helicobacter pylori in
the stomach, only a small fraction of colonized individuals develop this common malignancy …

[图书][B] Practical handbook of microbiology

LH Green, E Goldman - 2021 - books.google.com
Practical Handbook of Microbiology, 4th edition provides basic, clear and concise
knowledge and practical information about working with microorganisms. Useful to anyone …

THE PATHOGENESIS OF HELICOBACTER PYLORI–INDUCED GASTRO-DUODENAL DISEASES

JC Atherton - Annu. Rev. Pathol. Mech. Dis., 2006 - annualreviews.org
Helicobacter pylori is the main cause of peptic ulceration, distal gastric adenocarcinoma,
and gastric lymphoma. Only 15% of those colonized develop disease, and pathogenesis …

Type V protein secretion pathway: the autotransporter story

IR Henderson, F Navarro-Garcia… - Microbiology and …, 2004 - Am Soc Microbiol
Gram-negative bacteria possess an outer membrane layer which constrains uptake and
secretion of solutes and polypeptides. To overcome this barrier, bacteria have developed …

Helicobacter infection and gastric neoplasia

RM Peek Jr, JE Crabtree - The Journal of Pathology: A Journal …, 2006 - Wiley Online Library
Chronic gastritis induced by Helicobacter pylori is the strongest known risk factor for
adenocarcinoma of the distal stomach, yet only a minority of people who harbour this …

Helicobacter pylori and Interleukin 1 Genotyping: An Opportunity to Identify High-Risk Individuals for Gastric Carcinoma

C Figueiredo, JC Machado, P Pharoah… - Journal of the …, 2002 - academic.oup.com
Abstract Background: Both Helicobacter pylori genotype and host genetic polymorphisms
play a role in determining the clinical consequences of H. pylori infection. We investigated …

Clinical relevance of the cagA, vacA, and iceA status of Helicobacter pylori

LJ van Doorn, C Figueiredo, R Sanna, A Plaisier… - Gastroenterology, 1998 - Elsevier
Background & Aims: Clinical outcome of Helicobacter pylori infection may be associated
with specific virulence-associated bacterial genotypes. The aim of this study was to assess …

Relationship between Helicobacter pylori iceA, cagA, and vacA Status and Clinical Outcome: Studies in Four Different Countries

Y Yamaoka, T Kodama, O Gutierrez… - Journal of clinical …, 1999 - Am Soc Microbiol
There is continuing interest in identifying Helicobacter pylori virulence factors that might
predict the risk for symptomatic clinical outcomes. It has been proposed that iceA and cagA …

A proinflammatory genetic profile increases the risk for chronic atrophic gastritis and gastric carcinoma

JC Machado, C Figueiredo, P Canedo, P Pharoah… - Gastroenterology, 2003 - Elsevier
BACKGROUND & AIMS:: Pro-inflammatory polymorphisms within the genes interleukin (IL)-
1B and IL-1RN are associated with risk for gastric carcinoma (GC) in Helicobacter pylori …