Global burden of liver disease: 2023 update

H Devarbhavi, SK Asrani, JP Arab, YA Nartey… - Journal of …, 2023 - Elsevier
Liver disease accounts for two million deaths annually and is responsible for 4% of all
deaths (1 out of every 25 deaths worldwide); approximately two-thirds of all liver-related …

The intersection between alcohol-related liver disease and nonalcoholic fatty liver disease

LA Díaz, JP Arab, A Louvet, R Bataller… - Nature Reviews …, 2023 - nature.com
Nonalcoholic fatty liver disease (NAFLD) and alcohol-related liver disease (ALD) are the
leading causes of chronic liver disease worldwide. NAFLD and ALD share …

AASLD Practice Guidance on the clinical assessment and management of nonalcoholic fatty liver disease

ME Rinella, BA Neuschwander-Tetri, MS Siddiqui… - Hepatology, 2023 - journals.lww.com
Abbreviations: AASLD, American Association for the Study of Liver Diseases; AI, artificial
intelligence; ALT, alanine aminotransferase; AST, aspartate aminotransferase; AUROC …

MAFLD identifies patients with significant hepatic fibrosis better than NAFLD

S Yamamura, M Eslam, T Kawaguchi… - Liver …, 2020 - Wiley Online Library
Abstract Background & Aims Diagnostic criteria for metabolic associated fatty liver disease
(MAFLD) have been proposed, but not validated. We aimed to compare the diagnostic …

[PDF][PDF] Pathogenesis of nonalcoholic steatohepatitis: an overview

G Parthasarathy, X Revelo… - Hepatology …, 2020 - Wiley Online Library
Nonalcoholic fatty liver disease (NAFLD) is a heterogeneous group of liver diseases
characterized by the accumulation of fat in the liver. The heterogeneity of NAFLD is reflected …

Association of MAFLD with diabetes, chronic kidney disease, and cardiovascular disease: a 4.6-year cohort study in China

Y Liang, H Chen, Y Liu, X Hou, L Wei… - The Journal of …, 2022 - academic.oup.com
Context In 2020, the terminology of metabolic dysfunction–associated fatty liver disease
(MAFLD) was proposed to replace nonalcoholic fatty liver disease (NAFLD). Objectives This …

Does moderate alcohol consumption accelerate the progression of liver disease in NAFLD? A systematic review and narrative synthesis

H Jarvis, H O'Keefe, D Craig, D Stow, B Hanratty… - BMJ open, 2022 - bmjopen.bmj.com
Objectives Liver disease is a leading cause of premature death, partly driven by the
increasing incidence of non-alcohol-related fatty liver disease (NAFLD). Many people with a …

Natural history of NAFLD

R Pais, T Maurel - Journal of clinical medicine, 2021 - mdpi.com
The epidemiology and the current burden of chronic liver disease are changing globally,
with non-alcoholic fatty liver disease (NAFLD) becoming the most frequent cause of liver …

Regulation of cholesterol metabolism by phytochemicals derived from algae and edible mushrooms in non-alcoholic fatty liver disease

Y Eilam, N Pintel, H Khattib, N Shagug, R Taha… - International Journal of …, 2022 - mdpi.com
Cholesterol synthesis occurs in almost all cells, but mainly in hepatocytes in the liver.
Cholesterol is garnering increasing attention for its central role in various metabolic …

ACG clinical guideline: alcohol-associated liver disease

LL Jophlin, AK Singal, R Bataller… - Official journal of the …, 2024 - journals.lww.com
Alcohol-associated liver disease (ALD) is the most common cause of advanced hepatic
disease and frequent indication for liver transplantation worldwide. With harmful alcohol use …