Folding of the cerebral cortex is a fundamental milestone of mammalian brain evolution and
is associated with dramatic increases in size and complexity. New animal models, genetic …

The ability to model human brain development in vitro represents an important step in our
study of developmental processes and neurological disorders. Protocols that utilize human …

The neocortex has expanded during mammalian evolution. Overexpression studies in
developing mouse and ferret neocortex have implicated the human-specific gene …

The size and extent of folding of the mammalian cerebral cortex are important factors that
influence a species' cognitive abilities and sensorimotor skills. Studies in various animal …

Neural stem and progenitor cells have a central role in the development and evolution of the
mammalian neocortex. In this review, we first provide a set of criteria to classify the various …

Primary microcephaly (MCPH, for “microcephaly primary hereditary”) is a disorder of brain
development that results in a head circumference more than 3 standard deviations below …

Long-term ex vivo live imaging combined with unbiased sampling of cycling precursors
shows that macaque outer subventricular zone (OSVZ) includes four distinct basal radial …

Evolutionary expansion and complexification of the primate cerebral cortex are largely
linked to the emergence of the outer subventricular zone (OSVZ), a uniquely structured …

Subplate neurons have an essential role in cortical circuit formation. They are among the
earliest formed neurons of the cerebral cortex, are located at the junction of white and grey …

Evolution of the mammalian brain encompassed a remarkable increase in size of the
cerebral cortex, which includes tangential and radial expansion. However, the mechanisms …