There is abundant evidence that the pathophysiology of Parkinson's disease (PD) is not
confined to the nigrostriatal dopaminergic pathway but propagates along the cortico‐basal …

Parkinson's disease (PD) is a common neurodegenerative disorder. It has a delitescent
onset and a slow progress. The clinical manifestations of PD in patients are highly …

Parkinson's disease (PD) is a progressive, chronic, and neurodegenerative disorder that is
primarily diagnosed by clinical examinations and magnetic resonance imaging (MRI). In this …

Longitudinal connectivity studies might guide our understanding of the underlying
neurodegenerative processes. We report the results of a longitudinal study in patients at …

Heterogeneity between late-onset Parkinson's disease (LOPD) and early-onset Parkinson's
disease (EOPD) is mainly reflected in the following aspects including genetics, disease …

Background Apathy is among the most prevalent and incapacitating non-motor symptoms of
Parkinson's disease (PD). PD patients with apathy (PD-A) have been reported to have …

Purpose Whether the intrinsic functional connectivity pattern of the default mode network
(DMN) is involved in the progression of cognitive decline in Parkinson's disease (PD) …

Abstract Purpose of Review Advances in neuroimaging techniques pave a rich avenue for in
vivo progression biomarkers, which can objectively and noninvasively assess the long-term …

Purpose The aim of this study was to compare regional homogeneity (ReHo) changes in
Parkinson's disease mild cognitive impairment (PD-MCI) patients with respect to normal …

Hemiparkinsonism duration in patients with Parkinson's disease (PD) is a key time window
to study early pathology of PD. We aimed to comprehensively explore the alterations of …