[HTML][HTML] Mechanoresponsive regulation of myogenesis by the force-sensing transcriptional regulator Tono

X Zhang, J Avellaneda, ML Spletter, SB Lemke… - Current Biology, 2024 - cell.com
Muscle morphogenesis is a multi-step program, starting with myoblast fusion, followed by
myotube-tendon attachment and sarcomere assembly, with subsequent sarcomere …

Overexpression of miRNA-9 Generates Muscle Hypercontraction Through Translational Repression of Troponin-T in Drosophila melanogaster Indirect Flight Muscles

P Katti, D Thimmaya, A Madan… - G3: Genes, Genomes …, 2017 - academic.oup.com
MicroRNAs (miRNAs) are small noncoding endogenous RNAs, typically 21–23 nucleotides
long, that regulate gene expression, usually post-transcriptionally, by binding to the 3′-UTR …

Regular Exercise Rescues Heart Function Defects and Shortens the Lifespan of Drosophila Caused by dMnM Downregulation

W Gu, Q Li, M Ding, Y Cao, T Wang, S Zhang… - International Journal of …, 2022 - mdpi.com
Although studies have shown that myomesin 2 (MYOM2) mutations can lead to hypertrophic
cardiomyopathy (HCM), a common cardiovascular disease that has a serious impact on …

Regulation of fiber-specific actin expression by the Drosophila SRF ortholog Blistered

AA DeAguero, L Castillo, ST Oas, K Kiani… - …, 2019 - journals.biologists.com
Serum response factor (SRF) has an established role in controlling actin homeostasis in
mammalian cells, yet its role in non-vertebrate muscle development has remained …