Abstract l-asparaginase (EC 3.5. 1.1) is an important enzyme that has been purified and
characterized for over decades to study and evaluate its anti-carcinogenic activity against …

In the past decades, the production of biopharmaceuticals has gained high interest due to its
great sensitivity, specificity, and lower risk of negative effects to patients. Biopharmaceuticals …

Metabolic differences between normal and cancerous cells have been used as a point of
view for developing anticancer drugs. Some degrading enzymes of certain amino acids …

L-asparaginase, an amidohydrolase that catalyses break down of L-asparagine into aspartic
acid and ammonia, is one of the most prominent biopharmaceuticals. L-asparaginase (LA) …

Fungi, being obligate heterotrophs, are natural decomposers and elaborate a number of
enzymes. Currently, more than half of the industrial enzymes are of fungal origin and are …

L-asparaginase (EC 3.5. 1.1) is a well-known agent that prevents the formation of
acrylamide both in the food industry and against childhood acute lymphoblastic leukemia in …

Abstract L-Asparaginase (L-ASNase EC 3.5. 1.1) is considered as an important
biopharmaceutical drug enzyme in the treatment of childhood acute lymphoblastic leukemia …

Recombinant enzyme expression in Escherichia coli is one of the most popular methods to
produce bulk concentrations of protein product. However, this method is often limited by the …

Introduction: The bacterial enzyme has gained more attention in therapeutic application
because of the higher substrate specificity and longer half-life. L-asparaginase is an …

The enzyme L-asparaginase (L-ASNase) is used in the treatment of Acute Lymphoblastic
Leukemia. The preparations of this enzyme for clinical use are derived from bacterial …