The kainic acid model of temporal lobe epilepsy
M Lévesque, M Avoli - Neuroscience & Biobehavioral Reviews, 2013 - Elsevier
The kainic acid model of temporal lobe epilepsy has greatly contributed to the
understanding of the molecular, cellular and pharmacological mechanisms underlying …
understanding of the molecular, cellular and pharmacological mechanisms underlying …
Glutamatergic mechanisms associated with seizures and epilepsy
M Barker-Haliski, HS White - Cold Spring …, 2015 - perspectivesinmedicine.cshlp.org
Epilepsy is broadly characterized by aberrant neuronal excitability. Glutamate is the
predominant excitatory neurotransmitter in the adult mammalian brain; thus, much of past …
predominant excitatory neurotransmitter in the adult mammalian brain; thus, much of past …
Epileptogenesis
A Pitkänen, K Lukasiuk… - Cold Spring …, 2015 - perspectivesinmedicine.cshlp.org
Epileptogenesis is a chronic process that can be triggered by genetic or acquired factors,
and that can continue long after epilepsy diagnosis. In 2015, epileptogenesis is not a …
and that can continue long after epilepsy diagnosis. In 2015, epileptogenesis is not a …
The kainic acid models of temporal lobe epilepsy
E Rusina, C Bernard, A Williamson - Eneuro, 2021 - eneuro.org
Experimental models of epilepsy are useful to identify potential mechanisms of
epileptogenesis, seizure genesis, comorbidities, and treatment efficacy. The kainic acid (KA) …
epileptogenesis, seizure genesis, comorbidities, and treatment efficacy. The kainic acid (KA) …
Association of mortality and risk of epilepsy with type of acute symptomatic seizure after ischemic stroke and an updated prognostic model
Importance Acute symptomatic seizures occurring within 7 days after ischemic stroke may be
associated with an increased mortality and risk of epilepsy. It is unknown whether the type of …
associated with an increased mortality and risk of epilepsy. It is unknown whether the type of …
Animal models of temporal lobe epilepsy following systemic chemoconvulsant administration
In order to understand the pathophysiology of temporal lobe epilepsy (TLE), and thus to
develop new pharmacological treatments, in vivo animal models that present features …
develop new pharmacological treatments, in vivo animal models that present features …
Prevention or modification of epileptogenesis after brain insults: experimental approaches and translational research
Diverse brain insults, including traumatic brain injury, stroke, infections, tumors,
neurodegenerative diseases, and prolonged acute symptomatic seizures, such as complex …
neurodegenerative diseases, and prolonged acute symptomatic seizures, such as complex …
Experimental models of status epilepticus and neuronal injury for evaluation of therapeutic interventions
This article describes current experimental models of status epilepticus (SE) and neuronal
injury for use in the screening of new therapeutic agents. Epilepsy is a common neurological …
injury for use in the screening of new therapeutic agents. Epilepsy is a common neurological …
How can we identify ictal and interictal abnormal activity?
RS Fisher, HE Scharfman, M DeCurtis - … in clinical epileptology: A view from …, 2014 - Springer
Abstract The International League Against Epilepsy (ILAE) defined a seizure as “a transient
occurrence of signs and/or symptoms due to abnormal excessive or synchronous neuronal …
occurrence of signs and/or symptoms due to abnormal excessive or synchronous neuronal …
Mechanisms of physiological and epileptic HFO generation
JGR Jefferys, LM De La Prida, F Wendling… - Progress in …, 2012 - Elsevier
High frequency oscillations (HFO) have a variety of characteristics: band-limited or broad-
band, transient burst-like phenomenon or steady-state. HFOs may be encountered under …
band, transient burst-like phenomenon or steady-state. HFOs may be encountered under …