Aging is associated with an increased incidence of cardiovascular disease and thrombosis.
Platelets play a major role in maintaining hemostasis and in thrombus formation, making …

Many patients with end-stage heart disease die because of the scarcity of donor hearts. A
total artificial heart (TAH), an implantable machine that replaces the heart, has so far been …

Mechanically assisted circulation (MAC) sustains the blood circulation in the body of a
patients undergoing cardiac surgery with cardiopulmonary bypass (CPB) or on ventricular …

Objective: Hemorrhagic and thromboembolic complications are common during support with
extracorporeal membrane oxygenation (ECMO). As platelets play a pivotal role in …

Implantable Cardiovascular Therapeutic Devices (CTD), while lifesaving, impart
supraphysiologic shear stress to platelets, resulting in thrombotic and bleeding …

Background Non‐surgical bleeding (NSB) is a major complication after left ventricular assist
device (LVAD) implantation. It has been reported that non‐physiological shear stress …

Abstract Background and Aim Impella is frequently used to unload the left ventricle in
patients with cardiogenic shock on venoarterial extracorporeal membrane oxygenation (VA …

Objective Mechanical circulatory support (MCS) devices are widely used for cardiogenic
shock (CS). This network meta-analysis aims to evaluate which MCS strategy offers …

Abstract Clinopodium chinense (Benth.) O. Kuntze (C. chinense), a traditional Chinese
medicine with significant astringent and hemostatic properties, is mainly used to treat …

The regions with high non-physiological shear stresses (NPSS) are inevitable in blood-
contacting medical devices (BCMDs) used for mechanically assisted circulatory support …