Cold resistance of mammalian hibernators∼ a matter of ferroptosis?

M Sone, Y Yamaguchi - Frontiers in Physiology, 2024 - frontiersin.org
Most mammals adapt thermal physiology around 37° C and large deviations from their
range, as observed in severe hypothermia and hyperthermia, resulting in organ dysfunction …

Mitochondrial Targeting against Alzheimer's Disease: Lessons from Hibernation

CF de Veij Mestdagh, AB Smit, RH Henning… - Cells, 2023 - mdpi.com
Alzheimer's disease (AD) is the most common cause of dementia worldwide and yet remains
without effective therapy. Amongst the many proposed causes of AD, the mitochondrial …

Whole-genome sequencing of the invasive golden apple snail Pomacea canaliculata from Asia reveals rapid expansion and adaptive evolution

Y Lu, F Luo, A Zhou, C Yi, H Chen, J Li, Y Guo… - …, 2024 - academic.oup.com
Pomacea canaliculata, an invasive species native to South America, is recognized for its
broad geographic distribution and adaptability to a variety of ecological conditions. The …

Integrated Redox-Metabolic Orchestration Sustains Life in Hibernating Ground Squirrels

A Jankovic, A Kalezic, A Korac, B Buzadzic… - Antioxidants & Redox …, 2024 - liebertpub.com
Significance: The ultimate manifestations of life, birth, survival under various environmental
pressures and death are based on bioenergetics. Hibernation is a unique survival strategy …

[HTML][HTML] Effects of Hydrogen Sulfide at Normal Body Temperature and in the Cold on Isolated Tail and Carotid Arteries from Rats and TRPA1 Knockout and Wild-Type …

L Kelava, E Pakai, K Ogasawara, K Fekete, G Pozsgai… - Biomedicines, 2024 - mdpi.com
Background: Hydrogen sulfide (H2S) is a gasotransmitter that modulates vascular tone,
causing either vasodilation or vasoconstriction depending on the vascular bed, species, and …

Understanding the scientific validity of synthetic torpor for radiation research and extended space missions

AP Kokko, R Chowdhury, K Sherman… - Frontiers in Space …, 2024 - frontiersin.org
The idea of synthetic torpor, an artificial state resembling the hypo-metabolic state of
torpor/hibernation, has recently gained significant scientific attention. Building on pioneering …

Exploring molecular mechanisms of mouse hibernation for novel therapeutic angles in Alzheimer's disease

C de Veij Mestdagh - 2024 - research.rug.nl
Alzheimer's disease is the most prevalent neurodegenerative disease worldwide. In spite of
decades of research, there still is no effective treatment. This urges the need for novel …

[PDF][PDF] FACULDADE DE CIÊNCIAS E TECNOLOGIA

BRR Miguel - 2023 - estudogeral.uc.pt
Com o crescimento da população humana vem também a expansão da urbanização,
aumento da exploração de recursos e, consequentemente, o aumento das perturbações à …

Fizjologiczne znaczenie siarkowodoru i sposoby jego detekcji w układach biologicznych

D Słowiński, R Podsiadły - Progress, 2023 - ceeol.com
Siarkowodór (H2S) jest bezbarwnym gazem o nieprzyjemnym zapachu. Został uznany za
trzecią obok tlenku azotu (NO) i tlenku węgla (CO) gazową cząsteczkę sygnalizacyjną …

[PDF][PDF] Timeout with Torpor: History, Biology, and Future Medical Applications of a Survival Strategy

J Schafer - 2023 - escholarship.org
As human lifespans increase, technological advances push forward to continue this trend,
and human torpor has entered the discussion as a mode to improve longevity, especially by …