The application of circulating tumor cell and cell-free DNA liquid biopsies in ovarian cancer

A Balla, J Bhak, O Biró - Molecular and Cellular Probes, 2022 - Elsevier
Ovarian cancer is the deadliest gynecological cancer. 70% of the cases are diagnosed at
late stages with already developed metastases due to the absence of easily noticeable …

Plasma exosomal miR-1260a, miR-7977 and miR-192-5p as diagnostic biomarkers in epithelial ovarian cancer

L Chen, K Wang, L Li, B Zheng, Q Zhang, F Zhang… - Future …, 2022 - Taylor & Francis
Aim: The study aimed to clarify the diagnostic value of exosomal miRNAs in epithelial
ovarian cancer (EOC). Methods: Plasma exosomes were isolated from peripheral blood of …

The role of tumor-educated platelets in ovarian cancer: A comprehensive review and update

D Patel, S Thankachan, S Sreeram, KP Kavitha… - … -Research and Practice, 2023 - Elsevier
Platelets have recently surfaced as critical players in cancer metastasis and the local and
systemic responses to tumor growth. The emerging concept of" Tumor-educated platelets …

Serum anti-PDLIM1 autoantibody as diagnostic marker in ovarian cancer

C Qiu, Y Duan, B Wang, J Shi, P Wang, H Ye… - Frontiers in …, 2021 - frontiersin.org
Background Serum autoantibodies (AAbs) against tumor-associated antigens (TAAs) could
be useful biomarkers for cancer detection. This study aims to evaluate the diagnostic value …

Electrochemical Sensor for the Detection and Accurate Early Diagnosis of Ovarian Cancer

F Ge, W Ding, C Han, L Zhang, Q Liu, J Zhao, Z Luo… - ACS …, 2024 - ACS Publications
Ovarian cancer (OC) has the highest mortality rate among malignant tumors, primarily
because it is difficult to diagnose early. Exosomes, a type of extracellular vesicle rich in …

[HTML][HTML] Analysis of HOXA9 methylated ctDNA in ovarian cancer using sense-antisense measurement

L Faaborg, RF Andersen, M Waldstrøm, E Høgdall… - Clinica Chimica …, 2021 - Elsevier
DNA promoter methylation is an early event in tumorigenesis and holds promise as a
valuable marker in ovarian cancer (OC). It can be measured using circulating tumor specific …

Prognostic impact of circulating methylated homeobox A9 DNA in patients undergoing treatment for recurrent ovarian cancer

L Faaborg, RF Andersen, M Waldstrøm, JR Henriksen… - Cancers, 2022 - mdpi.com
Simple Summary Ovarian cancer remains a clinical challenge with considerable mortality.
Circulating tumor DNA (ctDNA) has been suggested as a prognostic biomarker and enables …

Mutation analysis of circulating tumor DNA and paired ascites and tumor tissues in ovarian cancer

X Jie, M Du, M Zhang, X Jin… - Experimental and …, 2022 - spandidos-publications.com
Circulating tumor DNA (ctDNA) is one conventional type of liquid biopsy that can be
collected to dynamically monitor disease status. However, its potential clinical value and …

Advancing cerumen analysis: exploring innovative vibrational spectroscopy techniques with respect to their potential as new point-of-care diagnostic tools

E Farnesi, M Calvarese, C Liu, C Messerschmidt… - Analyst, 2024 - pubs.rsc.org
Cerumen, commonly known as earwax, is a complex mixture composed of secretions from
ceruminous glands. These secretions are heterogeneous mixtures mainly composed of …

An overview of challenges associated with exosomal miRNA isolation toward liquid biopsy-based ovarian cancer detection

M Bhadra, M Sachan - Heliyon, 2024 - cell.com
As one of the deadliest gynecological cancers, ovarian cancer has been on the list. With
lesser-known symptoms and lack of an accurate detection method, it is still difficult to catch it …