Epstein Barr virus: development of vaccines and immune cell therapy for EBV-associated diseases

X Cui, CM Snapper - Frontiers in Immunology, 2021 - frontiersin.org
Epstein-Barr virus (EBV) is the first human tumor virus discovered and is strongly implicated
in the etiology of multiple lymphoid and epithelial cancers. Each year EBV associated …

The global landscape of EBV-associated tumors

C Shannon-Lowe, A Rickinson - Frontiers in oncology, 2019 - frontiersin.org
Epstein-Barr virus (EBV), a gamma-1 herpesvirus, is carried as a life-long asymptomatic
infection by the great majority of individuals in all human populations. Yet this seemingly …

Epstein–Barr virus infection and nasopharyngeal carcinoma

SW Tsao, CM Tsang, KW Lo - … Transactions of the …, 2017 - royalsocietypublishing.org
Epstein–Barr virus (EBV) is associated with multiple types of human cancer, including
lymphoid and epithelial cancers. The closest association with EBV infection is seen in …

NF-kB in development and progression of human cancer

X Dolcet, D Llobet, J Pallares, X Matias-Guiu - Virchows archiv, 2005 - Springer
The nuclear factor kB (NF-kB) comprises a family of transcription factors involved in the
regulation of a wide variety of biological responses. NF-kB plays a well-known function in …

Inflammation and cancer: how hot is the link?

BB Aggarwal, S Shishodia, SK Sandur… - Biochemical …, 2006 - Elsevier
Although inflammation has long been known as a localized protective reaction of tissue to
irritation, injury, or infection, characterized by pain, redness, swelling, and sometimes loss of …

Etiological factors of nasopharyngeal carcinoma

SW Tsao, YL Yip, CM Tsang, PS Pang, VMY Lau… - Oral oncology, 2014 - Elsevier
Nasopharyngeal carcinoma (NPC) is a common disease among southern Chinese. The
major etiological factors proposed for NPC pathogenesis include genetic susceptibility …

Functions of NF-κB1 and NF-κB2 in immune cell biology

S Beinke, SC Ley - Biochemical Journal, 2004 - portlandpress.com
Two members of the NF-κB (nuclear factor κB)/Rel transcription factor family, NF-κB1 and NF-
κB2, are produced as precursor proteins, NF-κB1 p105 and NF-κB2 p100 respectively …

[HTML][HTML] Translational genomics of nasopharyngeal cancer

CM Tsang, VWY Lui, JP Bruce, TJ Pugh… - Seminars in cancer biology, 2020 - Elsevier
Nasopharyngeal carcinoma (NPC), also named the Cantonese cancer, is a unique cancer
with strong etiological association with infection of the Epstein-Barr virus (EBV). With …

NF-kB's contribution to B cell fate decisions

C Guldenpfennig, E Teixeiro, M Daniels - Frontiers in immunology, 2023 - frontiersin.org
NF-κB signaling is essential to an effective innate and adaptive immune response. Many
immune-specific functional and developmental outcomes depend in large on NF-κB. The …

Focus on nasopharyngeal carcinoma

KW Lo, KF To, DP Huang - Cancer cell, 2004 - cell.com
A and B: Typical nasopharyngeal undifferentiated carcinoma (WHO type III). A: The
carcinoma cells exhibit prominent nucleoli and arrange in syncytial clusters. Dense …