Insects transmit the causative agents for such debilitating diseases as malaria, lymphatic
filariases, sleeping sickness, Chagas' disease, leishmaniasis, river blindness, Dengue, and …

Fasciolosis caused by Fasciola hepatica severely affects the efficiency of livestock
production systems worldwide. In addition to the economic impact inflicted on livestock …

Background Schistosomiasis—infection with helminth parasites in the genus Schistosoma,
including S. mansoni—is a widespread, devastating tropical disease affecting more than …

Schistosomiasis is a parasitic disease affecting over 200 million people currently treated
with one drug, praziquantel. A possible drug target is the seleno-protein thioredoxin …

Various strategies to deliver antimalarials using nanocarriers have been evaluated.
However, taking into account the peculiarities of malaria parasites, the focus is placed …

Background The cestode Echinococcus granulosus-the agent of cystic echinococcosis, a
zoonosis affecting humans and domestic animals worldwide-is an excellent model for the …

Platyhelminth parasites are a major health problem in developing countries. In contrast to
their mammalian hosts, platyhelminth thiol-disulfide redox homeostasis relies on linked …

The pseudodisaccharide mycothiol is present in millimolar levels as the dominant thiol in
most species of Actinomycetales. The primary role of mycothiol is to maintain the …

BACKGROUND: There are two, largely autonomous antioxidant pathways in many
organisms, one based on thioredoxin and one based on glutathione, with each pathway …

Schistosomiasis is a tropical disease associated with high morbidity and mortality, currently
affecting over 200 million people worldwide. Praziquantel is the only drug used to treat the …