Developments in the anticancer activity of structurally modified curcumin: An up-to-date review

FC Rodrigues, NVA Kumar, G Thakur - European journal of medicinal …, 2019 - Elsevier
Curcumin is a pharmacologically active polyphenol derived from the popular spice element-
Turmeric. The therapeutic activity of curcumin has been extensively investigated over the …

Recent advances in α, β-unsaturated carbonyl compounds as mitochondrial toxins

M Hossain, U Das, JR Dimmock - European Journal of Medicinal Chemistry, 2019 - Elsevier
Conjugated α, β-unsaturated ketones are very useful compounds associated with diverse
medicinal properties. This review outlines α, β-unsaturated ketones as candidate cytotoxic …

Tailored functionalization of natural phenols to improve biological activity

B Floris, P Galloni, V Conte, F Sabuzi - Biomolecules, 2021 - mdpi.com
Phenols are widespread in nature, being the major components of several plants and
essential oils. Natural phenols' anti-microbial, anti-bacterial, anti-oxidant, pharmacological …

CD36-fatty acid-mediated metastasis via the bidirectional interactions of cancer cells and macrophages

NE Zaidi, NAH Shazali, TC Leow, MA Osman… - Cells, 2022 - mdpi.com
Tumour heterogeneity refers to the complexity of cell subpopulations coexisting within the
tumour microenvironment (TME), such as proliferating tumour cells, tumour stromal cells and …

[HTML][HTML] Crosstalk between fatty acid metabolism and tumour-associated macrophages in cancer progression

NE Zaidi, NAH Shazali, TC Leow, MA Osman… - BioMedicine, 2022 - ncbi.nlm.nih.gov
Over the last few decades, cancer has been regarded as an independent and self sustaining
progression. The earliest hallmarks of cancer comprise of sustaining proliferative signalling …

The use of curcumin as an effective adjuvant to cancer therapy: A short review

H Bashang, S Tamma - Biotechnology and applied …, 2020 - Wiley Online Library
Turmeric (Curcuma longa) is a popular spice that has been used in Ayurvedic medicine for
its ability to treat various common ailments. There have been statistical correlations between …

Synthesis and bio-properties of 4-piperidone containing compounds as curcumin mimics

AS Girgis, P D'Arcy, DR Aboshouk, MS Bekheit - RSC advances, 2022 - pubs.rsc.org
The broad spectrum of curcumin's beneficial properties has encouraged medicinal
researchers to investigate its therapeutic efficacy against diverse diseases. The clinical …

[HTML][HTML] A comprehensive review on ethnobotany, nutritional values, phytochemistry and pharmacological attributes of ten Garcinia species of South-east Asia

A Paul, MK Zaman - South African Journal of Botany, 2022 - Elsevier
The tropical plants of Garcinia (Clusiaceae family) have been extensively used in folk
medicine apart from its limited use in the preparation of certain dishes. This paper aims to …

Physicochemical characterization, cytotoxic effect and toxicity evaluation of nanostructured lipid carrier loaded with eucalyptol

MNM Izham, Y Hussin, NFC Rahim, MNM Aziz… - … medicine and therapies, 2021 - Springer
Background Eucalyptol is an active compound of eucalyptus essential oil and was reported
to have many medical attributes including cytotoxic effect on breast cancer cells. However, it …

Anti-metastatic and anti-angiogenic effects of curcumin analog DK1 on human osteosarcoma cells in vitro

MNM Aziz, NFC Rahim, Y Hussin, SK Yeap… - Pharmaceuticals, 2021 - mdpi.com
Osteosarcoma (OS) is a life-threatening malignant bone tumor associated with poor
prognosis among children. The survival rate of the patient is still arguably low even with …