EMATOPOIESIS IS A quantitatively imposing pro-H cess in the adult, where about 3 x lo9
erythroid cells/kg and lo9 myeloid celis/kg are generated each day. Twenty-five years ago, in …

The colony-stimulating factors (CSFs) are a group of cytokines central to the hematopoiesis
of blood cells, the modulation of their functional responses, as well as the maintenance of …

Peptidyl-prolyl cis-trans isomerase (PPIase) catalyses the cis-trans isomerization of proline
imidic peptide bonds in oligopeptides and has been shown to accelerate the refolding of …

Granulocyte-colony stimulating factor (G-CSF) and granulocyte-macrophage-colony
stimulating factor (GM-CSF) belong to a family of glycoprotidic growth factors required for the …

Cytokinesp lay a vital role in coordinating immune and inflammatory responses. Unlike
growth factor receptors with a tyrosine kinase, cytokine receptors have no intrinsic tyrosine …

Transcription factors are key regulators of the pattern of gene expression in a cell and
directly control central processes such as proliferation, survival, self-renewal, and invasion …

Growth factor receptors play an important role in hematopoiesis. In order to further
understand the mechanisms directing the expression of these key regulators of …

Two cDNA clones encoding a receptor for human granulocyte‐macrophage colony‐
stimulating factor (hGM‐CSF‐R) were isolated by expression screening of a library made …

The colony-stimulating factors (CSFs) are the major regulators in the body of the production
and activity of two types of white blood cells--granulocytes and macrophages. CSFs are …

Some strains of human immunodeficiency virus type 1 (HIV-1) can infect primary monocytes
and monocyte-derived macrophages in vitro. In this report, the effect of cytokines on the …