The role of mTOR inhibitors in the management of posttransplant malignancy

AP Monaco - Transplantation, 2009 - journals.lww.com
Organ transplant recipients given mammalian target of rapamycin inhibitor (mTORi) have
reduced incidence of de novo posttransplant malignancies (dNPTMs). Posttransplant …

Post renal transplantation K aposi's sarcoma: a review of its epidemiology, pathogenesis, diagnosis, clinical aspects, and therapy

SM Hosseini‐Moghaddam… - Transplant Infectious …, 2012 - Wiley Online Library
Background Kaposi's sarcoma (KS) is a vascular malignancy primarily involving the skin.
This neoplasm occurs commonly in acquired immunodeficiency syndrome (AIDS) and post …

[HTML][HTML] Human herpesviruses 6, 7 and 8 in solid organ transplant recipients

RR Razonable - American Journal of Transplantation, 2013 - Elsevier
Human herpesviruses (HHV) 6 and 7 are ubiquitous infections that reactivate commonly in
transplant recipients. However, clinical diseases due to these viruses are reported only in …

Rapamycin blocks production of KSHV/HHV8: insights into the anti-tumor activity of an immunosuppressant drug

LA Nichols, LA Adang, DH Kedes - PloS one, 2011 - journals.plos.org
Background Infection with Kaposi's sarcoma-associated herpesvirus (KSHV/HHV8) often
results in the development of fatal tumors in immunocompromised patients. Studies of renal …

[HTML][HTML] HHV-6, HHV-7 and HHV-8 in solid organ transplant recipients

RR Razonable, DM Zerr… - American Journal of …, 2009 - Elsevier
Human herpesvirus 6 (HHV-6) and HHV-7 are lymphotropic β-herpesviruses that infect the
majority of humans during the first few years of life. Primary HHV-6 and HHV-7 infections …

Akt/TSC/mTOR activation by the KSHV G protein-coupled receptor: emerging insights into the molecular oncogenesis and treatment of Kaposi's sarcoma

S Montaner - Cell Cycle, 2007 - Taylor & Francis
Kaposi's sarcoma (KS) is an enigmatic vascular neoplasm that has reached epidemic
proportions in parts of the developing world and is a leading cause of morbidity and mortality …

[HTML][HTML] Human herpesvirus 6, 7 and 8 in solid organ transplantation

J Le, S Gantt… - American Journal of …, 2013 - Elsevier
Human herpesvirus (HHV)-6A, HHV-6B and HHV-7 are lymphotropic β-herpesviruses that
are almost universally acquired during the first few years of life and establish latency in …

Selection and use of immunosuppressive therapies after liver transplantation: current German practice

K Herzer, CP Strassburg, F Braun… - Clinical …, 2016 - Wiley Online Library
In recent years, immunosuppression (IS) after liver transplantation (LT) has become
increasingly diversified as the choice of agents has expanded and clinicians seek to …

[PDF][PDF] Conversion to sirolimus: a useful strategy for recalcitrant cutaneous viral warts in liver transplant recipient

S Dharancy, B Catteau, L Mortier… - Liver …, 2006 - Wiley Online Library
Dermatological complications following transplantation are very common and the majority of
immunosuppressed transplant recipients develop some to many warts due to human …

The change of immunosuppressive regimen from calcineurin inhibitors to mammalian target of rapamycin (mTOR) inhibitors and its effect on malignancy following …

N Saber-Moghaddam, H Nomani, A Sahebkar… - International …, 2019 - Elsevier
Malignancy is a significant cause of mortality after organ transplantation. There is an
increased rate of malignancy following heart transplantation (HTx) compared to the general …