Recent developments in multifunctional antimicrobial surfaces and applications toward advanced nitric oxide-based biomaterials

MK Chug, EJ Brisbois - ACS Materials Au, 2022 - ACS Publications
Implant-associated infections arising from biofilm development are known to have
detrimental effects with compromised quality of life for the patients, implying a progressing …

Nitric oxide releasing nanomaterials for cardiovascular applications

TA Tabish, MJ Crabtree, HE Townley… - Basic to Translational …, 2024 - jacc.org
A central paradigm of cardiovascular homeostasis is that impaired nitric oxide (NO)
bioavailability results in a wide array of cardiovascular dysfunction including incompetent …

Light-activated biodegradable covalent organic framework-integrated heterojunction for photodynamic, photothermal, and gaseous therapy of chronic wound infection

B Sun, Z Ye, M Zhang, Q Song, X Chu… - … Applied Materials & …, 2021 - ACS Publications
Chronic wound healing, impeded by bacterial infections and drug resistance, poses a threat
to global human health. Antibacterial phototherapy is an effective way to fight microbial …

Multifunctional Ag/ZnO/chitosan ternary bio-nanocomposites synthesized via laser ablation with enhanced optical, antibacterial, and catalytic characteristics

H Ali, AM Ismail, AA Menazea - Journal of Water Process Engineering, 2022 - Elsevier
Organic dyes and microorganisms in industrial wastewater have harmed both the
environment and human health. Herein, Ag/ZnO/chitosan (Ag/ZnO/Cs) ternary bio …

Smartphone compatible nitric oxide releasing insert to prevent catheter-associated infections

MK Chug, EJ Brisbois - Journal of Controlled Release, 2022 - Elsevier
A large fraction of nosocomial infections is associated with medical devices that are deemed
life-threatening in immunocompromised patients. Medical device-related infections are a …

Carbon nanotubes as a nitric oxide nano-reservoir improved the controlled release profile in 3D printed biodegradable vascular grafts

F Kabirian, P Baatsen, M Smet, A Shavandi, P Mela… - Scientific Reports, 2023 - nature.com
Small diameter vascular grafts (SDVGs) are associated with a high failure rate due to poor
endothelialization. The incorporation of a nitric oxide (NO) releasing system improves …

Nitric Oxide Release and Antibacterial Efficacy Analyses of S-Nitroso-N-Acetyl-Penicillamine Conjugated to Titanium Dioxide Nanoparticles

H Massoumi, R Kumar, MK Chug, Y Qian… - ACS applied bio …, 2022 - ACS Publications
Therapeutic agents can be linked to nanoparticles to fortify their selectivity and targeted
delivery while impeding systemic toxicity and efficacy loss. Titanium dioxide nanoparticles …

Pharmacological applications of nitric oxide-releasing biomaterials in human skin

AB Seabra, JC Pieretti, B de Melo Santana… - International Journal of …, 2023 - Elsevier
Nitric oxide (NO) is an important endogenous molecule that plays several roles in biological
systems. NO is synthesized in human skin by three isoforms of nitric oxide synthase (NOS) …

Tumor microenvironment-responsive multifunctional nanoplatform with selective toxicity for MRI-guided photothermal/photodynamic/nitric oxide combined cancer …

S Zhou, C Wu, P Shen, L Zhou, W Wang, K Lv… - Chemical Engineering …, 2024 - Elsevier
The trade-off in nanomaterials-based cancer therapy between safety and therapeutic
efficacy remains a significant challenge to overcome in the long run. In this context, we have …

Nitric oxide-releasing silicone oil with tunable payload for antibacterial applications

Y Qian, MK Chug, EJ Brisbois - ACS Applied Bio Materials, 2022 - ACS Publications
Bacterial infections are a hurdle to the application of medical devices, and in the United
States alone, more than one million infection cases are reported annually from indwelling …