Intracranial aneurysm subarachnoid hemorrhage (SAH) is a cerebrovascular disorder
associated with high overall mortality. Currently, the underlying mechanisms of pathological …

The perioperative neurocognitive disorders (PNDs) are one of the most common
complications in elderly patients characterized by various forms of cognitive decline after …

Background and Purpose: Neuronal pyroptosis is a type of regulated cell death triggered by
proinflammatory signals. CCR5 (CC chemokine receptor 5)-mediated inflammation is …

TBI has been one of the top causes of death and morbidity worldwide, yet despite enormous
efforts to discover neuroprotective therapeutics for this serious disease, no beneficial …

Parkinson's disease (PD) is characterized by the degeneration of dopaminergic nigrostriatal
neurons, which causes disabling motor disorders. Scientific findings support the role of …

Although M2 macrophages are involved in the orchestration of type 2 inflammation in
allergic diseases, the mechanisms underlying non-coding RNA (ncRNA)-mediated …

Luteolin (LUT) possesses multiple biologic functions and has beneficial effects for
cardiovascular and cerebral vascular diseases. Here, we investigated the protective effects …

Epigenetic modifications regulate critical biological processes that play a pivotal role in the
pathogenesis of cancer. Enhancer of Zeste Homolog 2 (EZH2), a subunit of the Polycomb …

Ischemic stroke is one of the major causes of morbidity and mortality worldwide.
Mitochondria play a vital role in the pathological processes of cerebral ischemic injury, but …

Interleukin 6 (IL-6) is a prominent proinflammatory cytokine. Neuroinflammation in general,
and IL-6 signaling in particular, appear to play a major role in the pathobiology and …