Y Liu, H Fu, T Wang - CNS Neuroscience & Therapeutics, 2022 - Wiley Online Library
The perioperative neurocognitive disorders (PNDs) are one of the most common complications in elderly patients characterized by various forms of cognitive decline after …
J Yan, W Xu, C Lenahan, L Huang, J Wen, G Li, X Hu… - Stroke, 2021 - Am Heart Assoc
Background and Purpose: Neuronal pyroptosis is a type of regulated cell death triggered by proinflammatory signals. CCR5 (CC chemokine receptor 5)-mediated inflammation is …
TBI has been one of the top causes of death and morbidity worldwide, yet despite enormous efforts to discover neuroprotective therapeutics for this serious disease, no beneficial …
D Mannino, SA Scuderi, G Casili, V Bova… - Journal of …, 2023 - Springer
Parkinson's disease (PD) is characterized by the degeneration of dopaminergic nigrostriatal neurons, which causes disabling motor disorders. Scientific findings support the role of …
S Wen, F Li, Y Tang, L Dong, Y He, Y Deng… - Frontiers in …, 2023 - frontiersin.org
Although M2 macrophages are involved in the orchestration of type 2 inflammation in allergic diseases, the mechanisms underlying non-coding RNA (ncRNA)-mediated …
ZH Zhang, JQ Liu, CD Hu, XT Zhao… - Oxidative Medicine …, 2021 - Wiley Online Library
Luteolin (LUT) possesses multiple biologic functions and has beneficial effects for cardiovascular and cerebral vascular diseases. Here, we investigated the protective effects …
Epigenetic modifications regulate critical biological processes that play a pivotal role in the pathogenesis of cancer. Enhancer of Zeste Homolog 2 (EZH2), a subunit of the Polycomb …
Ischemic stroke is one of the major causes of morbidity and mortality worldwide. Mitochondria play a vital role in the pathological processes of cerebral ischemic injury, but …
M Simon, A Grote - International Journal of Molecular Sciences, 2021 - mdpi.com
Interleukin 6 (IL-6) is a prominent proinflammatory cytokine. Neuroinflammation in general, and IL-6 signaling in particular, appear to play a major role in the pathobiology and …