Airborne particulate matter poses a serious threat to human health. Exposure to nanosized
(< 0.1 μm), vehicle-derived particulates may be hazardous due to their bioreactivity, their …

Although humans have been exposed to airborne nanosized particles (NSPs;< 100 nm)
throughout their evolutionary stages, such exposure has increased dramatically over the last …

Biologically formed nanoparticles of the strongly magnetic mineral, magnetite, were first
detected in the human brain over 20 y ago [Kirschvink JL, Kobayashi-Kirschvink A …

Engineered magnetic nanoparticles (MNPs) represent a cutting-edge tool in medicine
because they can be simultaneously functionalized and guided by a magnetic field. Use of …

For the last century, there has been great physiological interest in brain iron and its role in
brain function and disease. It is well known that iron accumulates in the brain for people with …

Altered iron metabolism has been hypothesized to be associated with Alzheimer's disease
pathology, and prior work has shown associations between iron load and beta amyloid …

Quantitative susceptibility mapping (QSM) has been used to study susceptibility changes
that may occur based on tissue composition and mineral deposition. Iron is a primary …

The brain has an unusually high concentration of iron, which is distributed in an unusual
pattern unlike that in any other organ. The physiological role of this iron and the reasons for …

Clinical magnetic resonance imaging (MRI) was introduced in the early 1980s and has
become a widely accepted and heavily utilized medical technology. This technique requires …

Abnormal accumulation of brain metals is a key feature of Alzheimer's disease (AD).
Formation of amyloid-β plaque cores (APC) is related to interactions with biometals …