Emodin-A natural anthraquinone derivative with diverse pharmacological activities

RB Semwal, DK Semwal, S Combrinck, A Viljoen - Phytochemistry, 2021 - Elsevier
Abstract Emodin (1, 3, 8-trihydroxy-6-methyl-anthraquinone) is a natural anthraquinone
derivative that is present in numerous globally renowned herbal medicines. It is recognised …

Recent advances and future prospects of phyto-phospholipid complexation technique for improving pharmacokinetic profile of plant actives

J Khan, A Alexander, S Saraf, S Saraf - Journal of controlled release, 2013 - Elsevier
The phyto-phospholipid complexation technique has emerged as one of the leading
methods of improving bioavailability of phytopharmaceuticals having poor competency of …

[PDF][PDF] An overview of advances in the standardization of herbal drugs

N Choudhary, BS Sekhon - Journal of Pharmaceutical Education and …, 2011 - far.fiocruz.br
Herbal formulations have reached extensive acceptability as therapeutic agents for several
diseases. The development of authentic analytical methods which can reliably profile the …

[HTML][HTML] Self nanoemulsifying drug delivery system of stabilized ellagic acid–phospholipid complex with improved dissolution and permeability

AM Avachat, VG Patel - Saudi Pharmaceutical Journal, 2015 - Elsevier
Ellagic acid (EA), a plant polyphenol known for its wide-range of health benefits has limited
use due to its low oral bioavailability. In this study, a new self-nanoemulsifying drug delivery …

Evidence based herbal drug standardization approach in coping with challenges of holistic management of diabetes: a dreadful lifestyle disorder of 21st century

R Chawla, P Thakur, A Chowdhry, S Jaiswal… - Journal of Diabetes & …, 2013 - Springer
Plants by virtue of its composition of containing multiple constituents developed during its
growth under various environmental stresses providing a plethora of chemical families with …

Critical review of lipid-based nanoparticles as carriers of neuroprotective drugs and extracts

F Fernandes, M Dias-Teixeira, C Delerue-Matos… - Nanomaterials, 2021 - mdpi.com
The biggest obstacle to the treatment of diseases that affect the central nervous system
(CNS) is the passage of drugs across the blood-brain barrier (BBB), a physical barrier that …

Drug solubilization by complexation

T Loftsson - International journal of pharmaceutics, 2017 - Elsevier
Drugs must possess some solubility in water to be therapeutically effective after oral or
topical administration to the eye, and drugs must be soluble to be formulated as aqueous …

Preparation and Evaluation of Phospholipid-Based Complex of Standardized Centella Extract (SCE) for the Enhanced Delivery of Phytoconstituents

SD Saoji, NA Raut, PW Dhore, CD Borkar… - The AAPS journal, 2016 - Springer
In the present study, a phospholipid-based complex of standardized Centella extract (SCE)
was developed with a goal of improving the bioavailability of its phytoconstituents. The SCE …

Cyclodextrin and phospholipid complexation in solubility and dissolution enhancement: a critical and meta-analysis

A Semalty - Expert opinion on drug delivery, 2014 - Taylor & Francis
Introduction: Poor solubility and dissolution of drugs are the major challenges in drug
formulation and delivery. In order to improve the solubility and dissolution profile of drugs …

Preparation, characterization and improved release profile of ibuprofen-phospholipid association

M Amirinejad, J Davoodi, MR Abbaspour… - Journal of drug delivery …, 2020 - Elsevier
Ibuprofen is a widely prescribed non-steroidal and anti-inflammatory drug, which is
practically insoluble in water and causes gastrointestinal (GI) side effects. Ibuprofen …