The flavonoid biosynthesis network in plants

W Liu, Y Feng, S Yu, Z Fan, X Li, J Li, H Yin - International journal of …, 2021 - mdpi.com
Flavonoids are an important class of secondary metabolites widely found in plants,
contributing to plant growth and development and having prominent applications in food and …

The NLRP3 inflammasome pathway: a review of mechanisms and inhibitors for the treatment of inflammatory diseases

HM Blevins, Y Xu, S Biby, S Zhang - Frontiers in aging neuroscience, 2022 - frontiersin.org
The NLRP3 inflammasome is a multiprotein complex that plays a pivotal role in regulating
the innate immune system and inflammatory signaling. Upon activation by PAMPs and …

[HTML][HTML] Therapeutic potential of flavonoids in cancer: ROS-mediated mechanisms

H Slika, H Mansour, N Wehbe, SA Nasser… - Biomedicine & …, 2022 - Elsevier
Cancer is a leading cause of morbidity and mortality around the globe. Reactive oxygen
species (ROS) play contradicting roles in cancer incidence and progression. Antioxidants …

Mechanism of epithelial‐mesenchymal transition in cancer and its regulation by natural compounds

HL Ang, CD Mohan, MK Shanmugam… - Medicinal research …, 2023 - Wiley Online Library
Epithelial‐mesenchymal transition (EMT) is a complex process with a primordial role in
cellular transformation whereby an epithelial cell transforms and acquires a mesenchymal …

[HTML][HTML] Antiproliferative and palliative activity of flavonoids in colorectal cancer

J Fernandez, B Silván, R Entrialgo-Cadierno… - Biomedicine & …, 2021 - Elsevier
Flavonoids are plant bioactive compounds of great interest in nutrition and pharmacology,
due to their remarkable properties as antioxidant, anti-inflammatory, antibacterial, antifungal …

The E-cadherin and N-cadherin switch in epithelial-to-mesenchymal transition: signaling, therapeutic implications, and challenges

CY Loh, JY Chai, TF Tang, WF Wong, G Sethi… - Cells, 2019 - mdpi.com
Epithelial-to-Mesenchymal Transition (EMT) has been shown to be crucial in tumorigenesis
where the EMT program enhances metastasis, chemoresistance and tumor stemness. Due …

Lagerstroemia speciosa (L.) Pers. triggers oxidative stress mediated apoptosis via intrinsic mitochondrial pathway in HepG2 cells

RS Thakur, E Devaraj - Environmental Toxicology, 2020 - Wiley Online Library
Hepatocellular carcinoma is the second leading cause of cancer‐related mortality
worldwide. Lagerstroemia speciosa Pers.(Lythraceae) commonly known as Banaba has …

Luteolin as a modulator of skin aging and inflammation

F Gendrisch, PR Esser, CM Schempp, U Wölfle - Biofactors, 2021 - Wiley Online Library
Luteolin belongs to the group of flavonoids and can be found in flowers, herbs, vegetables
and spices. It plays an important role in defending plants, for example against UV radiation …

Rapid quantitative detection of luteolin using an electrochemical sensor based on electrospinning of carbon nanofibers doped with single-walled carbon nanoangles

L Zhang, D Qin, J Feng, T Tang, H Cheng - Analytical Methods, 2023 - pubs.rsc.org
In this study, single-walled carbon nanoangles/carbon nanofibers (SWCNHs/CNFs) were
synthesized by electrospinning, followed by annealing in a N2 atmosphere. The synthesized …

Recent research on flavonoids and their biomedical applications

K Wen, X Fang, J Yang, Y Yao… - Current Medicinal …, 2021 - ingentaconnect.com
Flavonoids, commonly found in various plants, are a class of polyphenolic compounds
having a basic structural unit of 2-phenylchromone. Flavonoid compounds have attracted …