Application of Caenorhabditis elegans in Lipid Metabolism Research

L An, X Fu, J Chen, J Ma - International journal of molecular sciences, 2023 - mdpi.com
Over the last decade, the development and prevalence of obesity have posed a serious
public health risk, which has prompted studies on the regulation of adiposity. With the ease …

Lipid droplets and peroxisomes are co-regulated to drive lifespan extension in response to mono-unsaturated fatty acids

K Papsdorf, JW Miklas, A Hosseini, M Cabruja… - Nature cell …, 2023 - nature.com
Dietary mono-unsaturated fatty acids (MUFAs) are linked to longevity in several species. But
the mechanisms by which MUFAs extend lifespan remain unclear. Here we show that an …

Hydroxytyrosol promotes the mitochondrial function through activating mitophagy

Y Dong, M Yu, Y Wu, T Xia, L Wang, K Song, C Zhang… - Antioxidants, 2022 - mdpi.com
Emerging evidence suggests that mitochondrial dysfunction mediates the pathogenesis for
non-alcoholic fatty liver disease (NAFLD). Hydroxytyrosol (HT) is a key component of extra …

Oxidative stress can be attenuated by 4-PBA caused by high-fat or ammonia nitrogen in cultured spotted seabass: the mechanism is related to endoplasmic reticulum …

Y Dong, L Li, T Xia, L Wang, L Xiao, N Ding, Y Wu, K Lu - Antioxidants, 2022 - mdpi.com
Oxidative stress is a common phenomenon in aquaculture, which can be induced by
nutritional or environmental factors. Generally, oxidative stress causes poor growth …

Optimum relative frequency and fluctuating substrate selection in reinforcing anammox-mediated anabolic adaptation

Z Chen, F Meng, C Zhou, X Wu, C Jin - Water Research, 2023 - Elsevier
Adaptation to substrate fluctuations is a life actuality of microbes in global municipal
wastewater treatment plants (WWTPs). Yet there remains a lack of definite information on …

A novel N6-Deoxyadenine methyltransferase METL-9 modulates C. elegans immunity via dichotomous mechanisms

C Ma, T Xue, Q Peng, J Zhang, J Guan, W Ding, Y Li… - Cell Research, 2023 - nature.com
Abstract N 6-Methyldeoxyadenine (6mA) has been rediscovered as a DNA modification with
potential biological function in metazoans. However, the physiological function and …

Bifunctional fluorescent probe for the recognition of hydrazine and bisulfite in lipid droplets

Y Han, Y Huang, Q Lin, L Tang, G Yang, H Xin… - Sensors and Actuators B …, 2023 - Elsevier
Bifunctional fluorescent probes for recognizing different substances have important research
significance due to the wide variety of analytes. Here, a triphenylamine structural fluorescent …

4-PBA attenuates fat accumulation in cultured spotted seabass fed high-fat-diet via regulating endoplasmic reticulum stress

T Xia, YQ Liao, L Li, LY Sun, NS Ding, YL Wu, KL Lu - Metabolites, 2022 - mdpi.com
Excessive fat accumulation is a common phenomenon in cultured fish, which can cause
metabolic disease such as fatty liver. However, the relative regulatory approach remains to …

Polystyrene microbeads influence lipid storage distribution in C. elegans as revealed by coherent anti-Stokes Raman scattering (CARS) microscopy

H Fueser, C Pilger, C Kong, T Huser… - Environmental …, 2022 - Elsevier
The exposure of Caenorhabditis elegans to polystyrene (PS) beads of a wide range of sizes
impedes feeding, by reducing food consumption, and has been linked to inhibitory effects on …

Citrus aurantium L.'Daidai'physiological premature fruit drop relieves obesity in high-fat-diet-fed mice via modulating lipid metabolism and gut microbiota

M Peng, C Wang, Z Gao, F Fu, G Li, D Su, L Huang… - Food Bioscience, 2024 - Elsevier
Obesity is a global pandemic and public health crisis over decades. Except for physical
activity, dietary adjustments, pharmacotherapy and surgical interventions, prebiotics, which …